Mezler M - Search Results

1

Heterocomplex formation of 5-HT2A-mGlu2 and its relevance for cellular signaling cascades.

Delille HK, Becker JM, Burkhardt S, Bleher B, Terstappen GC, Schmidt M, Meyer AH, Unger L, Marek GJ, Mezler M. Delille HK, et al. Among authors: mezler m. Neuropharmacology. 2012 Jun;62(7):2184-91. doi: 10.1016/j.neuropharm.2012.01.010. Epub 2012 Jan 25. Neuropharmacology. 2012. PMID: 22300836

2

Inhibitors of GlyT1 affect glycine transport via discrete binding sites.

Mezler M, Hornberger W, Mueller R, Schmidt M, Amberg W, Braje W, Ochse M, Schoemaker H, Behl B. Mezler M, et al. Mol Pharmacol. 2008 Dec;74(6):1705-15. doi: 10.1124/mol.108.049312. Epub 2008 Sep 24. Mol Pharmacol. 2008. PMID: 18815213

3

LY-2140023, a prodrug of the group II metabotropic glutamate receptor agonist LY-404039 for the potential treatment of schizophrenia.

Mezler M, Geneste H, Gault L, Marek GJ. Mezler M, et al. Curr Opin Investig Drugs. 2010 Jul;11(7):833-45. Curr Opin Investig Drugs. 2010. PMID: 20571979 Clinical Trial.

4

Effects of a positive allosteric modulator of group II metabotropic glutamate receptors, LY487379, on cognitive flexibility and impulsive-like responding in rats.

Nikiforuk A, Popik P, Drescher KU, van Gaalen M, Relo AL, Mezler M, Marek G, Schoemaker H, Gross G, Bespalov A. Nikiforuk A, et al. Among authors: mezler m. J Pharmacol Exp Ther. 2010 Dec;335(3):665-73. doi: 10.1124/jpet.110.170506. Epub 2010 Aug 25. J Pharmacol Exp Ther. 2010. PMID: 20739457

5

Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: metabotropic glutamate 2/3 agonist modulation of ketamine-induced blood oxygenation level dependence signals.

Chin CL, Upadhyay J, Marek GJ, Baker SJ, Zhang M, Mezler M, Fox GB, Day M. Chin CL, et al. Among authors: mezler m. J Pharmacol Exp Ther. 2011 Mar;336(3):709-15. doi: 10.1124/jpet.110.173880. Epub 2010 Dec 20. J Pharmacol Exp Ther. 2011. PMID: 21172908

6

Identification and characterization of mGlu3 ligands using a high throughput FLIPR assay for detection of agonists, antagonists, and allosteric modulators.

Pratt SD, Mezler M, Geneste H, Bakker MH, Hajduk PJ, Gopalakrishnan SM. Pratt SD, et al. Among authors: mezler m. Comb Chem High Throughput Screen. 2011 Aug;14(7):631-41. doi: 10.2174/138620711796367184. Comb Chem High Throughput Screen. 2011. PMID: 21534916

7

Development and validation of a fluorescence-based HTS assay for the identification of P/Q-type calcium channel blockers.

Mezler M, Hermann D, Swensen AM, Draguhn A, Terstappen GC, Gross G, Schoemaker H, Freiberg G, Pratt S, Gopalakrishnan SM, Nimmrich V. Mezler M, et al. Comb Chem High Throughput Screen. 2012 Jun 1;15(5):372-85. doi: 10.2174/138620712800194503. Comb Chem High Throughput Screen. 2012. PMID: 22272661

8

The two faces of the pharmacological interaction of mGlu2 and 5-HT₂A - relevance of receptor heterocomplexes and interaction through functional brain pathways.

Delille HK, Mezler M, Marek GJ. Delille HK, et al. Among authors: mezler m. Neuropharmacology. 2013 Jul;70:296-305. doi: 10.1016/j.neuropharm.2013.02.005. Epub 2013 Mar 4. Neuropharmacology. 2013. PMID: 23466331 Review.

9

Trafficking of JC virus-like particles across the blood-brain barrier.

Ye D, Zimmermann T, Demina V, Sotnikov S, Ried CL, Rahn H, Stapf M, Untucht C, Rohe M, Terstappen GC, Wicke K, Mezler M, Manninga H, Meyer AH. Ye D, et al. Among authors: mezler m. Nanoscale Adv. 2021 Feb 9;3(9):2488-2500. doi: 10.1039/d0na00879f. eCollection 2021 May 4. Nanoscale Adv. 2021. PMID: 36134165 Free PMC article.

10

Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist.

El-Kouhen O, Lehto SG, Pan JB, Chang R, Baker SJ, Zhong C, Hollingsworth PR, Mikusa JP, Cronin EA, Chu KL, McGaraughty SP, Uchic ME, Miller LN, Rodell NM, Patel M, Bhatia P, Mezler M, Kolasa T, Zheng GZ, Fox GB, Stewart AO, Decker MW, Moreland RB, Brioni JD, Honore P. El-Kouhen O, et al. Among authors: mezler m. Br J Pharmacol. 2006 Nov;149(6):761-74. doi: 10.1038/sj.bjp.0706877. Epub 2006 Oct 3. Br J Pharmacol. 2006. PMID: 17016515 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

34 results

Search Page