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Fidaxomicin versus vancomycin for infection with Clostridium difficile in Europe, Canada, and the USA: a double-blind, non-inferiority, randomised controlled trial.
Cornely OA, Crook DW, Esposito R, Poirier A, Somero MS, Weiss K, Sears P, Gorbach S; OPT-80-004 Clinical Study Group. Cornely OA, et al. Among authors: sears p. Lancet Infect Dis. 2012 Apr;12(4):281-9. doi: 10.1016/S1473-3099(11)70374-7. Epub 2012 Feb 8. Lancet Infect Dis. 2012. PMID: 22321770 Clinical Trial.
Fidaxomicin versus vancomycin for Clostridium difficile infection.
Louie TJ, Miller MA, Mullane KM, Weiss K, Lentnek A, Golan Y, Gorbach S, Sears P, Shue YK; OPT-80-003 Clinical Study Group. Louie TJ, et al. Among authors: sears p. N Engl J Med. 2011 Feb 3;364(5):422-31. doi: 10.1056/NEJMoa0910812. N Engl J Med. 2011. PMID: 21288078 Free article. Clinical Trial.
A Randomized, Placebo-controlled Trial of Fidaxomicin for Prophylaxis of Clostridium difficile-associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation.
Mullane KM, Winston DJ, Nooka A, Morris MI, Stiff P, Dugan MJ, Holland H, Gregg K, Adachi JA, Pergam SA, Alexander BD, Dubberke ER, Broyde N, Gorbach SL, Sears PS. Mullane KM, et al. Among authors: sears ps. Clin Infect Dis. 2019 Jan 7;68(2):196-203. doi: 10.1093/cid/ciy484. Clin Infect Dis. 2019. PMID: 29893798 Free PMC article. Clinical Trial.
Response to Surawicz et al.
Gorbach S, DeRyke CA, Sears P. Gorbach S, et al. Among authors: sears p. Am J Gastroenterol. 2014 Oct;109(10):1684. doi: 10.1038/ajg.2014.224. Am J Gastroenterol. 2014. PMID: 25287090 No abstract available.
Safety and Pharmacokinetic Study of Fidaxomicin in Children With Clostridium difficile-Associated Diarrhea: A Phase 2a Multicenter Clinical Trial.
O'Gorman MA, Michaels MG, Kaplan SL, Otley A, Kociolek LK, Hoffenberg EJ, Kim KS, Nachman S, Pfefferkorn MD, Sentongo T, Sullivan JE, Sears P. O'Gorman MA, et al. Among authors: sears p. J Pediatric Infect Dis Soc. 2018 Aug 17;7(3):210-218. doi: 10.1093/jpids/pix037. J Pediatric Infect Dis Soc. 2018. PMID: 28575523 Clinical Trial.
Fidaxomicin inhibits spore production in Clostridium difficile.
Babakhani F, Bouillaut L, Gomez A, Sears P, Nguyen L, Sonenshein AL. Babakhani F, et al. Among authors: sears p. Clin Infect Dis. 2012 Aug;55 Suppl 2(Suppl 2):S162-9. doi: 10.1093/cid/cis453. Clin Infect Dis. 2012. PMID: 22752866 Free PMC article.
164 results