Lee JJ - Search Results

1

Identification of a cKit(+) colonic crypt base secretory cell that supports Lgr5(+) stem cells in mice.

Rothenberg ME, Nusse Y, Kalisky T, Lee JJ, Dalerba P, Scheeren F, Lobo N, Kulkarni S, Sim S, Qian D, Beachy PA, Pasricha PJ, Quake SR, Clarke MF. Rothenberg ME, et al. Among authors: lee jj. Gastroenterology. 2012 May;142(5):1195-1205.e6. doi: 10.1053/j.gastro.2012.02.006. Epub 2012 Feb 11. Gastroenterology. 2012. PMID: 22333952 Free PMC article.

2

Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog.

Lee JJ, von Kessler DP, Parks S, Beachy PA. Lee JJ, et al. Cell. 1992 Oct 2;71(1):33-50. doi: 10.1016/0092-8674(92)90264-d. Cell. 1992. PMID: 1394430

3

Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth.

Kim J, Tang JY, Gong R, Kim J, Lee JJ, Clemons KV, Chong CR, Chang KS, Fereshteh M, Gardner D, Reya T, Liu JO, Epstein EH, Stevens DA, Beachy PA. Kim J, et al. Among authors: lee jj. Cancer Cell. 2010 Apr 13;17(4):388-99. doi: 10.1016/j.ccr.2010.02.027. Cancer Cell. 2010. PMID: 20385363 Free PMC article.

4

Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector.

Kim J, Lee JJ, Kim J, Gardner D, Beachy PA. Kim J, et al. Among authors: lee jj. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13432-7. doi: 10.1073/pnas.1006822107. Epub 2010 Jul 12. Proc Natl Acad Sci U S A. 2010. PMID: 20624968 Free PMC article.

5

Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder.

Shin K, Lee J, Guo N, Kim J, Lim A, Qu L, Mysorekar IU, Beachy PA. Shin K, et al. Nature. 2011 Apr 7;472(7341):110-4. doi: 10.1038/nature09851. Epub 2011 Mar 9. Nature. 2011. PMID: 21389986 Free PMC article.

6

Stromal response to Hedgehog signaling restrains pancreatic cancer progression.

Lee JJ, Perera RM, Wang H, Wu DC, Liu XS, Han S, Fitamant J, Jones PD, Ghanta KS, Kawano S, Nagle JM, Deshpande V, Boucher Y, Kato T, Chen JK, Willmann JK, Bardeesy N, Beachy PA. Lee JJ, et al. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3091-100. doi: 10.1073/pnas.1411679111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024225 Free PMC article.

7

Control of inflammation by stromal Hedgehog pathway activation restrains colitis.

Lee JJ, Rothenberg ME, Seeley ES, Zimdahl B, Kawano S, Lu WJ, Shin K, Sakata-Kato T, Chen JK, Diehn M, Clarke MF, Beachy PA. Lee JJ, et al. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7545-E7553. doi: 10.1073/pnas.1616447113. Epub 2016 Nov 4. Proc Natl Acad Sci U S A. 2016. PMID: 27815529 Free PMC article.

8

Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis.

Ekker SC, McGrew LL, Lai CJ, Lee JJ, von Kessler DP, Moon RT, Beachy PA. Ekker SC, et al. Among authors: lee jj. Development. 1995 Aug;121(8):2337-47. doi: 10.1242/dev.121.8.2337. Development. 1995. PMID: 7671800

9

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling.

Porter JA, von Kessler DP, Ekker SC, Young KE, Lee JJ, Moses K, Beachy PA. Porter JA, et al. Among authors: lee jj. Nature. 1995 Mar 23;374(6520):363-6. doi: 10.1038/374363a0. Nature. 1995. PMID: 7885476

10

Autoproteolysis in hedgehog protein biogenesis.

Lee JJ, Ekker SC, von Kessler DP, Porter JA, Sun BI, Beachy PA. Lee JJ, et al. Science. 1994 Dec 2;266(5190):1528-37. doi: 10.1126/science.7985023. Science. 1994. PMID: 7985023

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