Huang G - Search Results

1

Inhibition of mycobacterial infection by the tumor suppressor PTEN.

Huang G, Redelman-Sidi G, Rosen N, Glickman MS, Jiang X. Huang G, et al. J Biol Chem. 2012 Jun 29;287(27):23196-202. doi: 10.1074/jbc.M112.351940. Epub 2012 May 21. J Biol Chem. 2012. PMID: 22613768 Free PMC article.

2

Crucial role of the C-terminus of PTEN in antagonizing NEDD4-1-mediated PTEN ubiquitination and degradation.

Wang X, Shi Y, Wang J, Huang G, Jiang X. Wang X, et al. Among authors: huang g. Biochem J. 2008 Sep 1;414(2):221-9. doi: 10.1042/BJ20080674. Biochem J. 2008. PMID: 18498243

3

The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity.

Huang G, Towe CW, Choi L, Yonekawa Y, Bommeljé CC, Bains S, Rechler W, Hao B, Ramanathan Y, Singh B. Huang G, et al. J Biol Chem. 2015 Jan 2;290(1):296-309. doi: 10.1074/jbc.M114.560169. Epub 2014 Nov 19. J Biol Chem. 2015. PMID: 25411243 Free PMC article.

4

SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.

Kim AY, Bommeljé CC, Lee BE, Yonekawa Y, Choi L, Morris LG, Huang G, Kaufman A, Ryan RJ, Hao B, Ramanathan Y, Singh B. Kim AY, et al. Among authors: huang g. J Biol Chem. 2008 Nov 28;283(48):33211-20. doi: 10.1074/jbc.M804440200. Epub 2008 Sep 30. J Biol Chem. 2008. PMID: 18826954 Free PMC article.

5

Squamous Cell Carcinoma-related Oncogene (SCCRO) Family Members Regulate Cell Growth and Proliferation through Their Cooperative and Antagonistic Effects on Cullin Neddylation.

Fu W, Sun J, Huang G, Liu JC, Kaufman A, Ryan RJ, Ramanathan SY, Venkatesh T, Singh B. Fu W, et al. Among authors: huang g. J Biol Chem. 2016 Mar 18;291(12):6200-17. doi: 10.1074/jbc.M115.692756. Epub 2016 Jan 20. J Biol Chem. 2016. PMID: 26792857 Free PMC article.

6

SCCRO3 (DCUN1D3) antagonizes the neddylation and oncogenic activity of SCCRO (DCUN1D1).

Huang G, Stock C, Bommeljé CC, Weeda VB, Shah K, Bains S, Buss E, Shaha M, Rechler W, Ramanathan SY, Singh B. Huang G, et al. J Biol Chem. 2014 Dec 12;289(50):34728-42. doi: 10.1074/jbc.M114.585505. Epub 2014 Oct 27. J Biol Chem. 2014. PMID: 25349211 Free PMC article.

7

Squamous cell carcinoma-related oncogene (SCCRO) neddylates Cul3 protein to selectively promote midbody localization and activity of Cul3^KLHL21 protein complex during abscission.

Huang G, Kaufman AJ, Xu K, Manova K, Singh B. Huang G, et al. J Biol Chem. 2017 Sep 15;292(37):15254-15265. doi: 10.1074/jbc.M117.778530. Epub 2017 Jun 15. J Biol Chem. 2017. PMID: 28620047 Free PMC article.

8

SCCRO (DCUN1D1) promotes nuclear translocation and assembly of the neddylation E3 complex.

Huang G, Kaufman AJ, Ramanathan Y, Singh B. Huang G, et al. J Biol Chem. 2011 Mar 25;286(12):10297-304. doi: 10.1074/jbc.M110.203729. Epub 2011 Jan 19. J Biol Chem. 2011. PMID: 21247897 Free PMC article.

9

Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization.

Huang G, Kaufman AJ, Ryan RJH, Romin Y, Huryn L, Bains S, Manova-Todorova K, Morris PL, Hunnicutt GR, Adelman CA, Petrini JHJ, Ramanathan Y, Singh B. Huang G, et al. PLoS One. 2019 Jan 17;14(1):e0209995. doi: 10.1371/journal.pone.0209995. eCollection 2019. PLoS One. 2019. PMID: 30653527 Free PMC article.

10

Oncogenic function of SCCRO5/DCUN1D5 requires its Neddylation E3 activity and nuclear localization.

Bommeljé CC, Weeda VB, Huang G, Shah K, Bains S, Buss E, Shaha M, Gönen M, Ghossein R, Ramanathan SY, Singh B. Bommeljé CC, et al. Among authors: huang g. Clin Cancer Res. 2014 Jan 15;20(2):372-81. doi: 10.1158/1078-0432.CCR-13-1252. Epub 2013 Nov 5. Clin Cancer Res. 2014. PMID: 24192928 Free PMC article.

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