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Are sirtuins viable targets for improving healthspan and lifespan?
Baur JA, Ungvari Z, Minor RK, Le Couteur DG, de Cabo R. Baur JA, et al. Among authors: ungvari z. Nat Rev Drug Discov. 2012 Jun 1;11(6):443-61. doi: 10.1038/nrd3738. Nat Rev Drug Discov. 2012. PMID: 22653216 Free PMC article. Review.
Mitochondrial protection by resveratrol.
Ungvari Z, Sonntag WE, de Cabo R, Baur JA, Csiszar A. Ungvari Z, et al. Exerc Sport Sci Rev. 2011 Jul;39(3):128-32. doi: 10.1097/JES.0b013e3182141f80. Exerc Sport Sci Rev. 2011. PMID: 21383627 Free PMC article. Review.
SRT1720 improves survival and healthspan of obese mice.
Minor RK, Baur JA, Gomes AP, Ward TM, Csiszar A, Mercken EM, Abdelmohsen K, Shin YK, Canto C, Scheibye-Knudsen M, Krawczyk M, Irusta PM, Martín-Montalvo A, Hubbard BP, Zhang Y, Lehrmann E, White AA, Price NL, Swindell WR, Pearson KJ, Becker KG, Bohr VA, Gorospe M, Egan JM, Talan MI, Auwerx J, Westphal CH, Ellis JL, Ungvari Z, Vlasuk GP, Elliott PJ, Sinclair DA, de Cabo R. Minor RK, et al. Among authors: ungvari z. Sci Rep. 2011;1:70. doi: 10.1038/srep00070. Epub 2011 Aug 18. Sci Rep. 2011. PMID: 22355589 Free PMC article.
Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.
Mattison JA, Wang M, Bernier M, Zhang J, Park SS, Maudsley S, An SS, Santhanam L, Martin B, Faulkner S, Morrell C, Baur JA, Peshkin L, Sosnowska D, Csiszar A, Herbert RL, Tilmont EM, Ungvari Z, Pearson KJ, Lakatta EG, de Cabo R. Mattison JA, et al. Among authors: ungvari z. Cell Metab. 2014 Jul 1;20(1):183-90. doi: 10.1016/j.cmet.2014.04.018. Epub 2014 May 29. Cell Metab. 2014. PMID: 24882067 Free PMC article.
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, Swindell WR, Kamara D, Minor RK, Perez E, Jamieson HA, Zhang Y, Dunn SR, Sharma K, Pleshko N, Woollett LA, Csiszar A, Ikeno Y, Le Couteur D, Elliott PJ, Becker KG, Navas P, Ingram DK, Wolf NS, Ungvari Z, Sinclair DA, de Cabo R. Pearson KJ, et al. Among authors: ungvari z. Cell Metab. 2008 Aug;8(2):157-68. doi: 10.1016/j.cmet.2008.06.011. Epub 2008 Jul 3. Cell Metab. 2008. PMID: 18599363 Free PMC article.
Role of endothelial NAD+ deficiency in age-related vascular dysfunction.
Csiszar A, Tarantini S, Yabluchanskiy A, Balasubramanian P, Kiss T, Farkas E, Baur JA, Ungvari Z. Csiszar A, et al. Among authors: ungvari z. Am J Physiol Heart Circ Physiol. 2019 Jun 1;316(6):H1253-H1266. doi: 10.1152/ajpheart.00039.2019. Epub 2019 Mar 15. Am J Physiol Heart Circ Physiol. 2019. PMID: 30875255 Free PMC article. Review.
Mechanisms of vascular aging: new perspectives.
Ungvari Z, Kaley G, de Cabo R, Sonntag WE, Csiszar A. Ungvari Z, et al. J Gerontol A Biol Sci Med Sci. 2010 Oct;65(10):1028-41. doi: 10.1093/gerona/glq113. Epub 2010 Jun 24. J Gerontol A Biol Sci Med Sci. 2010. PMID: 20576649 Free PMC article. Review.
Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice.
Tarantini S, Valcarcel-Ares MN, Toth P, Yabluchanskiy A, Tucsek Z, Kiss T, Hertelendy P, Kinter M, Ballabh P, Süle Z, Farkas E, Baur JA, Sinclair DA, Csiszar A, Ungvari Z. Tarantini S, et al. Among authors: ungvari z. Redox Biol. 2019 Jun;24:101192. doi: 10.1016/j.redox.2019.101192. Epub 2019 Apr 10. Redox Biol. 2019. PMID: 31015147 Free PMC article.
330 results