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Caspase-6 and neurodegeneration.
Graham RK, Ehrnhoefer DE, Hayden MR. Graham RK, et al. Among authors: ehrnhoefer de. Trends Neurosci. 2011 Dec;34(12):646-56. doi: 10.1016/j.tins.2011.09.001. Epub 2011 Oct 22. Trends Neurosci. 2011. PMID: 22018804 Review.
Palmitoylation of caspase-6 by HIP14 regulates its activation.
Skotte NH, Sanders SS, Singaraja RR, Ehrnhoefer DE, Vaid K, Qiu X, Kannan S, Verma C, Hayden MR. Skotte NH, et al. Among authors: ehrnhoefer de. Cell Death Differ. 2017 Mar;24(3):433-444. doi: 10.1038/cdd.2016.139. Epub 2016 Dec 2. Cell Death Differ. 2017. PMID: 27911442 Free PMC article.
Compromised IGF signaling causes caspase-6 activation in Huntington disease.
Skotte NH, Pouladi MA, Ehrnhoefer DE, Huynh K, Qiu X, Nielsen SMB, Nielsen TT, Nørremølle A, Hayden MR. Skotte NH, et al. Among authors: ehrnhoefer de. Exp Neurol. 2020 Oct;332:113396. doi: 10.1016/j.expneurol.2020.113396. Epub 2020 Jul 2. Exp Neurol. 2020. PMID: 32622701
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin.
Okamoto S, Pouladi MA, Talantova M, Yao D, Xia P, Ehrnhoefer DE, Zaidi R, Clemente A, Kaul M, Graham RK, Zhang D, Vincent Chen HS, Tong G, Hayden MR, Lipton SA. Okamoto S, et al. Among authors: ehrnhoefer de. Nat Med. 2009 Dec;15(12):1407-13. doi: 10.1038/nm.2056. Epub 2009 Nov 15. Nat Med. 2009. PMID: 19915593 Free PMC article.
Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice.
Uribe V, Wong BK, Graham RK, Cusack CL, Skotte NH, Pouladi MA, Xie Y, Feinberg K, Ou Y, Ouyang Y, Deng Y, Franciosi S, Bissada N, Spreeuw A, Zhang W, Ehrnhoefer DE, Vaid K, Miller FD, Deshmukh M, Howland D, Hayden MR. Uribe V, et al. Among authors: ehrnhoefer de. Hum Mol Genet. 2012 May 1;21(9):1954-67. doi: 10.1093/hmg/dds005. Epub 2012 Jan 18. Hum Mol Genet. 2012. PMID: 22262731 Free PMC article.
40 results