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Antigen availability determines CD8⁺ T cell-dendritic cell interaction kinetics and memory fate decisions.
Henrickson SE, Perro M, Loughhead SM, Senman B, Stutte S, Quigley M, Alexe G, Iannacone M, Flynn MP, Omid S, Jesneck JL, Imam S, Mempel TR, Mazo IB, Haining WN, von Andrian UH. Henrickson SE, et al. Among authors: loughhead sm. Immunity. 2013 Sep 19;39(3):496-507. doi: 10.1016/j.immuni.2013.08.034. Immunity. 2013. PMID: 24054328 Free PMC article.
Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8+ T Cell Responses with Antitumor Activity.
Booty MG, Hlavaty KA, Stockmann A, Ozay EI, Smith C, Tian L, How E, Subramanya D, Venkitaraman A, Yee C, Pryor O, Volk K, Blagovic K, Vicente-Suarez I, Yarar D, Myint M, Merino A, Chow J, Abdeljawad T, An H, Liu S, Mao S, Heimann M, Talarico L, Jacques MK, Chong E, Pomerance L, Gonzalez JT, von Andrian UH, Jensen KF, Langer R, Knoetgen H, Trumpfheller C, Umaña P, Bernstein H, Sharei A, Loughhead SM. Booty MG, et al. Among authors: loughhead sm. J Immunol. 2022 Feb 15;208(4):929-940. doi: 10.4049/jimmunol.2100656. Epub 2022 Jan 28. J Immunol. 2022. PMID: 35091434 Free PMC article.
Targeted Delivery of Immunomodulators to Lymph Nodes.
Azzi J, Yin Q, Uehara M, Ohori S, Tang L, Cai K, Ichimura T, McGrath M, Maarouf O, Kefaloyianni E, Loughhead S, Petr J, Sun Q, Kwon M, Tullius S, von Andrian UH, Cheng J, Abdi R. Azzi J, et al. Cell Rep. 2016 May 10;15(6):1202-13. doi: 10.1016/j.celrep.2016.04.007. Epub 2016 Apr 28. Cell Rep. 2016. PMID: 27134176 Free PMC article.
Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice.
Liu Y, Belkina NV, Park C, Nambiar R, Loughhead SM, Patino-Lopez G, Ben-Aissa K, Hao JJ, Kruhlak MJ, Qi H, von Andrian UH, Kehrl JH, Tyska MJ, Shaw S. Liu Y, et al. Among authors: loughhead sm. Blood. 2012 Jan 12;119(2):445-53. doi: 10.1182/blood-2011-07-368860. Epub 2011 Nov 21. Blood. 2012. PMID: 22106344 Free PMC article.
Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex.
Prüss H, Tedeschi A, Thiriot A, Lynch L, Loughhead SM, Stutte S, Mazo IB, Kopp MA, Brommer B, Blex C, Geurtz LC, Liebscher T, Niedeggen A, Dirnagl U, Bradke F, Volz MS, DeVivo MJ, Chen Y, von Andrian UH, Schwab JM. Prüss H, et al. Among authors: loughhead sm. Nat Neurosci. 2017 Nov;20(11):1549-1559. doi: 10.1038/nn.4643. Epub 2017 Sep 18. Nat Neurosci. 2017. PMID: 28920935
Engineered red blood cells (activating antigen carriers) drive potent T cell responses and tumor regression in mice.
Blagovic K, Smith CK, Ramakrishnan A, Moore L, Soto DR, Thompson Z, Stockmann AP, Kruszelnicki S, Thakkar A, Murray J, Torres S, Wondimagegnhu B, Yi R, Dadgar M, Paracha AM, Page C, Clear L, Chaudhry OA, Myint M, Bridgen DT, Gilbert JB, Seidl KJ, Sharei A, Loughhead S, Bernstein H, Yarar D. Blagovic K, et al. Front Immunol. 2022 Oct 3;13:1015585. doi: 10.3389/fimmu.2022.1015585. eCollection 2022. Front Immunol. 2022. PMID: 36263022 Free PMC article.
13 results