Esmon CT - Search Results

1

Circulating nucleosomes and severity of illness in children suffering from meningococcal sepsis treated with protein C.

Zeerleder S, Stephan F, Emonts M, de Kleijn ED, Esmon CT, Varadi K, Hack CE, Hazelzet JA. Zeerleder S, et al. Among authors: esmon ct. Crit Care Med. 2012 Dec;40(12):3224-9. doi: 10.1097/CCM.0b013e318265695f. Crit Care Med. 2012. PMID: 22932399 Clinical Trial.

2

Endogenous protein C has a protective role during Gram-negative pneumosepsis (melioidosis).

Kager LM, Wiersinga WJ, Roelofs JJ, Meijers JC, Zeerleder SS, Esmon CT, van't Veer C, van der Poll T. Kager LM, et al. Among authors: esmon ct. J Thromb Haemost. 2013 Feb;11(2):282-92. doi: 10.1111/jth.12094. J Thromb Haemost. 2013. PMID: 23216621 Free article.

3

A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation.

Vincent JL, Ramesh MK, Ernest D, LaRosa SP, Pachl J, Aikawa N, Hoste E, Levy H, Hirman J, Levi M, Daga M, Kutsogiannis DJ, Crowther M, Bernard GR, Devriendt J, Puigserver JV, Blanzaco DU, Esmon CT, Parrillo JE, Guzzi L, Henderson SJ, Pothirat C, Mehta P, Fareed J, Talwar D, Tsuruta K, Gorelick KJ, Osawa Y, Kaul I. Vincent JL, et al. Among authors: esmon ct. Crit Care Med. 2013 Sep;41(9):2069-79. doi: 10.1097/CCM.0b013e31828e9b03. Crit Care Med. 2013. PMID: 23979365 Clinical Trial.

4

The protein C pathway.

Esmon C. Esmon C. Crit Care Med. 2000 Sep;28(9 Suppl):S44-8. doi: 10.1097/00003246-200009001-00010. Crit Care Med. 2000. PMID: 11007197 Review.

5

Why do animal models (sometimes) fail to mimic human sepsis?

Esmon CT. Esmon CT. Crit Care Med. 2004 May;32(5 Suppl):S219-22. doi: 10.1097/01.ccm.0000127036.27343.48. Crit Care Med. 2004. PMID: 15118521 Review.

6

Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis).

Kager LM, Schouten M, Wiersinga WJ, de Boer JD, Lattenist LC, Roelofs JJ, Meijers JC, Levi M, Dondorp AM, Esmon CT, van 't Veer C, van der Poll T. Kager LM, et al. Among authors: esmon ct. PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2306. doi: 10.1371/journal.pntd.0002306. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23875041 Free PMC article.

7

A comparative study of the protein C pathway in septic and nonseptic patients with organ failure.

Borgel D, Bornstain C, Reitsma PH, Lerolle N, Gandrille S, Dali-Ali F, Esmon CT, Fagon JY, Aiach M, Diehl JL. Borgel D, et al. Among authors: esmon ct. Am J Respir Crit Care Med. 2007 Nov 1;176(9):878-85. doi: 10.1164/rccm.200611-1692OC. Epub 2007 Aug 2. Am J Respir Crit Care Med. 2007. PMID: 17673691

8

The normal role of Activated Protein C in maintaining homeostasis and its relevance to critical illness.

Esmon CT. Esmon CT. Crit Care. 2001;5(2):S7-12. doi: 10.1186/cc1333. Crit Care. 2001. PMID: 11379986 Free PMC article. Review.

9

Protein C pathway in sepsis.

Esmon CT. Esmon CT. Ann Med. 2002;34(7-8):598-605. doi: 10.1080/078538902321117823. Ann Med. 2002. PMID: 12553500 Review.

10

Clinical expert round table discussion (session 3) at the Margaux Conference on Critical Illness: the role of activated protein C in severe sepsis.

Bernard G, Artigas A, Dellinger P, Esmon C, Faist E, Faust SN, Fischer CJ, Fumagalli R, grinnell BW, Sprung C. Bernard G, et al. Crit Care Med. 2001 Jul;29(7 Suppl):S75-7. doi: 10.1097/00003246-200107001-00025. Crit Care Med. 2001. PMID: 11445738 Review. No abstract available.

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