Biesiada J - Search Results

1

On setting up and assessing docking simulations for virtual screening.

Biesiada J, Porollo A, Meller J. Biesiada J, et al. Methods Mol Biol. 2012;928:1-16. doi: 10.1007/978-1-62703-008-3_1. Methods Mol Biol. 2012. PMID: 22956129

2

Survey of public domain software for docking simulations and virtual screening.

Biesiada J, Porollo A, Velayutham P, Kouril M, Meller J. Biesiada J, et al. Hum Genomics. 2011 Jul;5(5):497-505. doi: 10.1186/1479-7364-5-5-497. Hum Genomics. 2011. PMID: 21807604 Free PMC article. Review.

3

Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.

Evelyn CR, Duan X, Biesiada J, Seibel WL, Meller J, Zheng Y. Evelyn CR, et al. Among authors: biesiada j. Chem Biol. 2014 Dec 18;21(12):1618-28. doi: 10.1016/j.chembiol.2014.09.018. Epub 2014 Nov 20. Chem Biol. 2014. PMID: 25455859 Free PMC article.

4

Combined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzyme.

Evelyn CR, Biesiada J, Duan X, Tang H, Shang X, Papoian R, Seibel WL, Nelson S, Meller J, Zheng Y. Evelyn CR, et al. Among authors: biesiada j. J Biol Chem. 2015 May 15;290(20):12879-98. doi: 10.1074/jbc.M114.634493. Epub 2015 Mar 30. J Biol Chem. 2015. PMID: 25825487 Free PMC article.

5

Genetic risk signatures of opioid-induced respiratory depression following pediatric tonsillectomy.

Biesiada J, Chidambaran V, Wagner M, Zhang X, Martin LJ, Meller J, Sadhasivam S. Biesiada J, et al. Pharmacogenomics. 2014 Nov;15(14):1749-1762. doi: 10.2217/pgs.14.137. Pharmacogenomics. 2014. PMID: 25493568 Free PMC article.

6

Significant variation between SNP-based HLA imputations in diverse populations: the last mile is the hardest.

Pappas DJ, Lizee A, Paunic V, Beutner KR, Motyer A, Vukcevic D, Leslie S, Biesiada J, Meller J, Taylor KD, Zheng X, Zhao LP, Gourraud PA, Hollenbach JA, Mack SJ, Maiers M. Pappas DJ, et al. Among authors: biesiada j. Pharmacogenomics J. 2018 May 22;18(3):367-376. doi: 10.1038/tpj.2017.7. Epub 2017 Apr 25. Pharmacogenomics J. 2018. PMID: 28440342 Free PMC article.

7

Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation.

Bosco EE, Kumar S, Marchioni F, Biesiada J, Kordos M, Szczur K, Meller J, Seibel W, Mizrahi A, Pick E, Filippi MD, Zheng Y. Bosco EE, et al. Among authors: biesiada j. Chem Biol. 2012 Feb 24;19(2):228-42. doi: 10.1016/j.chembiol.2011.12.017. Chem Biol. 2012. PMID: 22365606 Free PMC article.

8

Predicting mechanism of action of cellular perturbations with pathway activity signatures.

Ren Y, Sivaganesan S, Clark NA, Zhang L, Biesiada J, Niu W, Plas DR, Medvedovic M. Ren Y, et al. Among authors: biesiada j. Bioinformatics. 2020 Sep 15;36(18):4781-4788. doi: 10.1093/bioinformatics/btaa590. Bioinformatics. 2020. PMID: 32653926 Free PMC article.

9

Connecting omics signatures and revealing biological mechanisms with iLINCS.

Pilarczyk M, Fazel-Najafabadi M, Kouril M, Shamsaei B, Vasiliauskas J, Niu W, Mahi N, Zhang L, Clark NA, Ren Y, White S, Karim R, Xu H, Biesiada J, Bennett MF, Davidson SE, Reichard JF, Roberts K, Stathias V, Koleti A, Vidovic D, Clarke DJB, Schürer SC, Ma'ayan A, Meller J, Medvedovic M. Pilarczyk M, et al. Among authors: biesiada j. Nat Commun. 2022 Aug 9;13(1):4678. doi: 10.1038/s41467-022-32205-3. Nat Commun. 2022. PMID: 35945222 Free PMC article.

10

Targeting substrate-site in Jak2 kinase prevents emergence of genetic resistance.

Kesarwani M, Huber E, Kincaid Z, Evelyn CR, Biesiada J, Rance M, Thapa MB, Shah NP, Meller J, Zheng Y, Azam M. Kesarwani M, et al. Among authors: biesiada j. Sci Rep. 2015 Sep 30;5:14538. doi: 10.1038/srep14538. Sci Rep. 2015. PMID: 26419724 Free PMC article.

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