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An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma.
Abraham J, Chua YX, Glover JM, Tyner JW, Loriaux MM, Kilcoyne A, Giles FJ, Nelon LD, Carew JS, Ouyang Y, Michalek JE, Pal R, Druker BJ, Rubin BP, Keller C. Abraham J, et al. Among authors: druker bj. Biochem Biophys Res Commun. 2012 Sep 28;426(3):363-8. doi: 10.1016/j.bbrc.2012.08.092. Epub 2012 Aug 30. Biochem Biophys Res Commun. 2012. PMID: 22960170 Free PMC article.
c-CBL is not required for leukemia induction by Bcr-Abl in mice.
Dinulescu DM, Wood LJ, Shen L, Loriaux M, Corless CL, Gross AW, Ren R, Deininger MW, Druker BJ. Dinulescu DM, et al. Among authors: druker bj. Oncogene. 2003 Dec 4;22(55):8852-60. doi: 10.1038/sj.onc.1206892. Oncogene. 2003. PMID: 14654781
Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies.
Schittenhelm MM, Shiraga S, Schroeder A, Corbin AS, Griffith D, Lee FY, Bokemeyer C, Deininger MW, Druker BJ, Heinrich MC. Schittenhelm MM, et al. Among authors: druker bj. Cancer Res. 2006 Jan 1;66(1):473-81. doi: 10.1158/0008-5472.CAN-05-2050. Cancer Res. 2006. PMID: 16397263
Activating alleles of JAK3 in acute megakaryoblastic leukemia.
Walters DK, Mercher T, Gu TL, O'Hare T, Tyner JW, Loriaux M, Goss VL, Lee KA, Eide CA, Wong MJ, Stoffregen EP, McGreevey L, Nardone J, Moore SA, Crispino J, Boggon TJ, Heinrich MC, Deininger MW, Polakiewicz RD, Gilliland DG, Druker BJ. Walters DK, et al. Among authors: druker bj. Cancer Cell. 2006 Jul;10(1):65-75. doi: 10.1016/j.ccr.2006.06.002. Cancer Cell. 2006. PMID: 16843266 Free article.
Characterization of murine JAK2V617F-positive myeloproliferative disease.
Bumm TG, Elsea C, Corbin AS, Loriaux M, Sherbenou D, Wood L, Deininger J, Silver RT, Druker BJ, Deininger MW. Bumm TG, et al. Among authors: druker bj. Cancer Res. 2006 Dec 1;66(23):11156-65. doi: 10.1158/0008-5472.CAN-06-2210. Cancer Res. 2006. PMID: 17145859
Applying the discovery of the Philadelphia chromosome.
Sherbenou DW, Druker BJ. Sherbenou DW, et al. Among authors: druker bj. J Clin Invest. 2007 Aug;117(8):2067-74. doi: 10.1172/JCI31988. J Clin Invest. 2007. PMID: 17671641 Free PMC article. Review.
438 results