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An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma.
Abraham J, Chua YX, Glover JM, Tyner JW, Loriaux MM, Kilcoyne A, Giles FJ, Nelon LD, Carew JS, Ouyang Y, Michalek JE, Pal R, Druker BJ, Rubin BP, Keller C. Abraham J, et al. Among authors: michalek je. Biochem Biophys Res Commun. 2012 Sep 28;426(3):363-8. doi: 10.1016/j.bbrc.2012.08.092. Epub 2012 Aug 30. Biochem Biophys Res Commun. 2012. PMID: 22960170 Free PMC article.
Dynamic and nuclear expression of PDGFRα and IGF-1R in alveolar Rhabdomyosarcoma.
Aslam MI, Hettmer S, Abraham J, Latocha D, Soundararajan A, Huang ET, Goros MW, Michalek JE, Wang S, Mansoor A, Druker BJ, Wagers AJ, Tyner JW, Keller C. Aslam MI, et al. Among authors: michalek je. Mol Cancer Res. 2013 Nov;11(11):1303-13. doi: 10.1158/1541-7786.MCR-12-0598. Epub 2013 Aug 8. Mol Cancer Res. 2013. PMID: 23928059 Free PMC article.
PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma.
Taniguchi E, Nishijo K, McCleish AT, Michalek JE, Grayson MH, Infante AJ, Abboud HE, Legallo RD, Qualman SJ, Rubin BP, Keller C. Taniguchi E, et al. Among authors: michalek je. Oncogene. 2008 Nov 20;27(51):6550-60. doi: 10.1038/onc.2008.255. Epub 2008 Aug 4. Oncogene. 2008. PMID: 18679424 Free PMC article.
Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma.
Kikuchi K, Soundararajan A, Zarzabal LA, Weems CR, Nelon LD, Hampton ST, Michalek JE, Rubin BP, Fields AP, Keller C. Kikuchi K, et al. Among authors: michalek je. Oncogene. 2013 Jan 17;32(3):286-95. doi: 10.1038/onc.2012.46. Epub 2012 Feb 20. Oncogene. 2013. PMID: 22349825 Free PMC article.
IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma.
Hosoyama T, Aslam MI, Abraham J, Prajapati SI, Nishijo K, Michalek JE, Zarzabal LA, Nelon LD, Guttridge DC, Rubin BP, Keller C. Hosoyama T, et al. Among authors: michalek je. Clin Cancer Res. 2011 May 1;17(9):2757-66. doi: 10.1158/1078-0432.CCR-10-3445. Clin Cancer Res. 2011. PMID: 21536546 Free PMC article.
Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma.
Kikuchi K, Taniguchi E, Chen HH, Svalina MN, Abraham J, Huang ET, Nishijo K, Davis S, Louden C, Zarzabal LA, Recht O, Bajwa A, Berlow N, Suelves M, Perkins SL, Meltzer PS, Mansoor A, Michalek JE, Chen Y, Rubin BP, Keller C. Kikuchi K, et al. Among authors: michalek je. Skelet Muscle. 2013 Nov 25;3(1):27. doi: 10.1186/2044-5040-3-27. Skelet Muscle. 2013. PMID: 24274149 Free PMC article.
Lineage of origin in rhabdomyosarcoma informs pharmacological response.
Abraham J, Nuñez-Álvarez Y, Hettmer S, Carrió E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, Brack AS, Wagers AJ, Rando TA, Capecchi MR, Marini FC, Ehler BR, Zarzabal LA, Goros MW, Michalek JE, Meltzer PS, Langenau DM, LeGallo RD, Mansoor A, Chen Y, Suelves M, Rubin BP, Keller C. Abraham J, et al. Among authors: michalek je. Genes Dev. 2014 Jul 15;28(14):1578-91. doi: 10.1101/gad.238733.114. Genes Dev. 2014. PMID: 25030697 Free PMC article.
215 results