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A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site.
Nürnberg ST, Rendon A, Smethurst PA, Paul DS, Voss K, Thon JN, Lloyd-Jones H, Sambrook JG, Tijssen MR; HaemGen Consortium; Italiano JE Jr, Deloukas P, Gottgens B, Soranzo N, Ouwehand WH. Nürnberg ST, et al. Among authors: smethurst pa. Blood. 2012 Dec 6;120(24):4859-68. doi: 10.1182/blood-2012-01-401893. Epub 2012 Sep 12. Blood. 2012. PMID: 22972982 Free PMC article.
The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression.
Joutsi-Korhonen L, Smethurst PA, Rankin A, Gray E, IJsseldijk M, Onley CM, Watkins NA, Williamson LM, Goodall AH, de Groot PG, Farndale RW, Ouwehand WH. Joutsi-Korhonen L, et al. Among authors: smethurst pa. Blood. 2003 Jun 1;101(11):4372-9. doi: 10.1182/blood-2002-08-2591. Epub 2003 Jan 30. Blood. 2003. PMID: 12560230 Free article.
Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody.
Smethurst PA, Joutsi-Korhonen L, O'Connor MN, Wilson E, Jennings NS, Garner SF, Zhang Y, Knight CG, Dafforn TR, Buckle A, IJsseldijk MJ, De Groot PG, Watkins NA, Farndale RW, Ouwehand WH. Smethurst PA, et al. Blood. 2004 Feb 1;103(3):903-11. doi: 10.1182/blood-2003-01-0308. Epub 2003 Sep 22. Blood. 2004. PMID: 14504096 Free article.
Monoclonal antibody therapies in transfusion medicine.
Ouwehand WH, Watkins NA, Garner SF, Smethurst PA. Ouwehand WH, et al. Among authors: smethurst pa. Vox Sang. 2004 Jul;87 Suppl 2:151-4. doi: 10.1111/j.1741-6892.2004.00490.x. Vox Sang. 2004. PMID: 15209903 Review. No abstract available.
48 results