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Quantitative approaches for assessing dose-response relationships in genetic toxicology studies.
Gollapudi BB, Johnson GE, Hernandez LG, Pottenger LH, Dearfield KL, Jeffrey AM, Julien E, Kim JH, Lovell DP, Macgregor JT, Moore MM, van Benthem J, White PA, Zeiger E, Thybaud V. Gollapudi BB, et al. Among authors: lovell dp. Environ Mol Mutagen. 2013 Jan;54(1):8-18. doi: 10.1002/em.21727. Epub 2012 Sep 18. Environ Mol Mutagen. 2013. PMID: 22987251
Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment.
Johnson GE, Soeteman-Hernández LG, Gollapudi BB, Bodger OG, Dearfield KL, Heflich RH, Hixon JG, Lovell DP, MacGregor JT, Pottenger LH, Thompson CM, Abraham L, Thybaud V, Tanir JY, Zeiger E, van Benthem J, White PA. Johnson GE, et al. Among authors: lovell dp. Environ Mol Mutagen. 2014 Oct;55(8):609-23. doi: 10.1002/em.21870. Epub 2014 May 6. Environ Mol Mutagen. 2014. PMID: 24801602 Free PMC article.
Strategies in case of positive in vivo results in genotoxicity testing.
Thybaud V, Macgregor JT, Müller L, Crebelli R, Dearfield K, Douglas G, Farmer PB, Gocke E, Hayashi M, Lovell DP, Lutz WK, Marzin D, Moore M, Nohmi T, Phillips DH, Van Benthem J. Thybaud V, et al. Among authors: lovell dp. Mutat Res. 2011 Aug 16;723(2):121-8. doi: 10.1016/j.mrgentox.2010.09.002. Epub 2010 Sep 17. Mutat Res. 2011. PMID: 20854927
A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.
Kirkland D, Levy DD, LeBaron MJ, Aardema MJ, Beevers C, Bhalli J, Douglas GR, Escobar PA, Farabaugh CS, Guerard M, Johnson GE, Kulkarni R, Le Curieux F, Long AS, Lott J, Lovell DP, Luijten M, Marchetti F, Nicolette JJ, Pfuhler S, Roberts DJ, Stankowski LF Jr, Thybaud V, Weiner SK, Williams A, Witt KL, Young R. Kirkland D, et al. Among authors: lovell dp. Mutat Res Genet Toxicol Environ Mutagen. 2019 Mar;839:21-35. doi: 10.1016/j.mrgentox.2019.01.007. Epub 2019 Jan 18. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 30744809 Free PMC article.
Human blood PIG-A mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra- and inter-subject variation.
Torous DK, Avlasevich SL, Khattab MG, Baig A, Saubermann LJ, Chen Y, Bemis JC, Lovell DP, Walker VE, MacGregor JT, Dertinger SD. Torous DK, et al. Among authors: lovell dp. Environ Mol Mutagen. 2020 Oct;61(8):807-819. doi: 10.1002/em.22393. Epub 2020 Jul 27. Environ Mol Mutagen. 2020. PMID: 32572998 Free PMC article.
The in vivo Pig-a assay: A report of the International Workshop On Genotoxicity Testing (IWGT) Workgroup.
Gollapudi BB, Lynch AM, Heflich RH, Dertinger SD, Dobrovolsky VN, Froetschl R, Horibata K, Kenyon MO, Kimoto T, Lovell DP, Stankowski LF Jr, White PA, Witt KL, Tanir JY. Gollapudi BB, et al. Among authors: lovell dp. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:23-35. doi: 10.1016/j.mrgentox.2014.09.007. Epub 2014 Sep 26. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953398
Analysis of negative historical control group data from the in vitro micronucleus assay using TK6 cells.
Lovell DP, Fellows M, Marchetti F, Christiansen J, Elhajouji A, Hashimoto K, Kasamoto S, Li Y, Masayasu O, Moore MM, Schuler M, Smith R, Stankowski LF Jr, Tanaka J, Tanir JY, Thybaud V, Van Goethem F, Whitwell J. Lovell DP, et al. Mutat Res Genet Toxicol Environ Mutagen. 2018 Jan;825:40-50. doi: 10.1016/j.mrgentox.2017.10.006. Epub 2017 Nov 10. Mutat Res Genet Toxicol Environ Mutagen. 2018. PMID: 29307374 Free article.
Assessment of systemic genetic damage in pediatric inflammatory bowel disease.
Baig A, Avlasevich SL, Torous DK, Bemis JC, Saubermann LJ, Lovell DP, MacGregor JT, Dertinger SD. Baig A, et al. Among authors: lovell dp. Environ Mol Mutagen. 2020 Nov;61(9):901-909. doi: 10.1002/em.22403. Epub 2020 Aug 22. Environ Mol Mutagen. 2020. PMID: 32761646 Free PMC article.
85 results