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Deep sequencing of antiviral T-cell responses to HCMV and EBV in humans reveals a stable repertoire that is maintained for many years.
Klarenbeek PL, Remmerswaal EB, ten Berge IJ, Doorenspleet ME, van Schaik BD, Esveldt RE, Koch SD, ten Brinke A, van Kampen AH, Bemelman FJ, Tak PP, Baas F, de Vries N, van Lier RA. Klarenbeek PL, et al. Among authors: doorenspleet me. PLoS Pathog. 2012 Sep;8(9):e1002889. doi: 10.1371/journal.ppat.1002889. Epub 2012 Sep 27. PLoS Pathog. 2012. PMID: 23028307 Free PMC article.
Clonal evolution of CD8+ T cell responses against latent viruses: relationship among phenotype, localization, and function.
Remmerswaal EB, Klarenbeek PL, Alves NL, Doorenspleet ME, van Schaik BD, Esveldt RE, Idu MM, van Leeuwen EM, van der Bom-Baylon N, van Kampen AH, Koch SD, Pircher H, Bemelman FJ, Ten Brinke A, Baas F, Ten Berge IJ, van Lier RA, de Vries N. Remmerswaal EB, et al. Among authors: doorenspleet me. J Virol. 2015 Jan;89(1):568-80. doi: 10.1128/JVI.02003-14. Epub 2014 Oct 22. J Virol. 2015. PMID: 25339770 Free PMC article.
Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction.
Klarenbeek PL, Doorenspleet ME, Esveldt RE, van Schaik BD, Lardy N, van Kampen AH, Tak PP, Plenge RM, Baas F, de Bakker PI, de Vries N. Klarenbeek PL, et al. Among authors: doorenspleet me. PLoS One. 2015 Oct 30;10(10):e0140815. doi: 10.1371/journal.pone.0140815. eCollection 2015. PLoS One. 2015. PMID: 26517366 Free PMC article.
Non-response to rituximab therapy in rheumatoid arthritis is associated with incomplete disruption of the B cell receptor repertoire.
Pollastro S, Klarenbeek PL, Doorenspleet ME, van Schaik BDC, Esveldt REE, Thurlings RM, Boumans MJH, Gerlag DM, Tak PP, Vos K, Baas F, van Kampen AHC, de Vries N. Pollastro S, et al. Among authors: doorenspleet me. Ann Rheum Dis. 2019 Oct;78(10):1339-1345. doi: 10.1136/annrheumdis-2018-214898. Epub 2019 Jun 19. Ann Rheum Dis. 2019. PMID: 31217169 Free PMC article.
Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease.
Klarenbeek PL, de Hair MJ, Doorenspleet ME, van Schaik BD, Esveldt RE, van de Sande MG, Cantaert T, Gerlag DM, Baeten D, van Kampen AH, Baas F, Tak PP, de Vries N. Klarenbeek PL, et al. Among authors: doorenspleet me. Ann Rheum Dis. 2012 Jun;71(6):1088-93. doi: 10.1136/annrheumdis-2011-200612. Epub 2012 Jan 31. Ann Rheum Dis. 2012. PMID: 22294635
Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing.
Reshetova P, van Schaik BD, Klarenbeek PL, Doorenspleet ME, Esveldt RE, Tak PP, Guikema JE, de Vries N, van Kampen AH. Reshetova P, et al. Among authors: doorenspleet me. Front Immunol. 2017 Mar 6;8:221. doi: 10.3389/fimmu.2017.00221. eCollection 2017. Front Immunol. 2017. PMID: 28321219 Free PMC article.
Dominant B cell receptor clones in peripheral blood predict onset of arthritis in individuals at risk for rheumatoid arthritis.
Tak PP, Doorenspleet ME, de Hair MJH, Klarenbeek PL, van Beers-Tas MH, van Kampen AHC, van Schaardenburg D, Gerlag DM, Baas F, de Vries N. Tak PP, et al. Among authors: doorenspleet me. Ann Rheum Dis. 2017 Nov;76(11):1924-1930. doi: 10.1136/annrheumdis-2017-211351. Epub 2017 Aug 8. Ann Rheum Dis. 2017. PMID: 28790026 Free PMC article. Retracted.
25 results