Molenaar JJ - Search Results

1

LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.

Molenaar JJ, Domingo-Fernández R, Ebus ME, Lindner S, Koster J, Drabek K, Mestdagh P, van Sluis P, Valentijn LJ, van Nes J, Broekmans M, Haneveld F, Volckmann R, Bray I, Heukamp L, Sprüssel A, Thor T, Kieckbusch K, Klein-Hitpass L, Fischer M, Vandesompele J, Schramm A, van Noesel MM, Varesio L, Speleman F, Eggert A, Stallings RL, Caron HN, Versteeg R, Schulte JH. Molenaar JJ, et al. Nat Genet. 2012 Nov;44(11):1199-206. doi: 10.1038/ng.2436. Epub 2012 Oct 7. Nat Genet. 2012. PMID: 23042116

2

Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma.

Molenaar JJ, van Sluis P, Boon K, Versteeg R, Caron HN. Molenaar JJ, et al. Genes Chromosomes Cancer. 2003 Mar;36(3):242-9. doi: 10.1002/gcc.10166. Genes Chromosomes Cancer. 2003. PMID: 12557224

3

ArrayCGH-based classification of neuroblastoma into genomic subgroups.

Michels E, Vandesompele J, De Preter K, Hoebeeck J, Vermeulen J, Schramm A, Molenaar JJ, Menten B, Marques B, Stallings RL, Combaret V, Devalck C, De Paepe A, Versteeg R, Eggert A, Laureys G, Van Roy N, Speleman F. Michels E, et al. Among authors: molenaar jj. Genes Chromosomes Cancer. 2007 Dec;46(12):1098-108. doi: 10.1002/gcc.20496. Genes Chromosomes Cancer. 2007. PMID: 17823929

4

Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma.

Molenaar JJ, Ebus ME, Koster J, van Sluis P, van Noesel CJ, Versteeg R, Caron HN. Molenaar JJ, et al. Cancer Res. 2008 Apr 15;68(8):2599-609. doi: 10.1158/0008-5472.CAN-07-5032. Cancer Res. 2008. PMID: 18413728 Free article.

5

Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells.

Molenaar JJ, Ebus ME, Geerts D, Koster J, Lamers F, Valentijn LJ, Westerhout EM, Versteeg R, Caron HN. Molenaar JJ, et al. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12968-73. doi: 10.1073/pnas.0901418106. Epub 2009 Jun 12. Proc Natl Acad Sci U S A. 2009. PMID: 19525400 Free PMC article.

6

Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells.

Molenaar JJ, Ebus ME, Koster J, Santo E, Geerts D, Versteeg R, Caron HN. Molenaar JJ, et al. Oncogene. 2010 May 6;29(18):2739-45. doi: 10.1038/onc.2010.21. Epub 2010 Feb 15. Oncogene. 2010. PMID: 20154722

7

Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells.

Verissimo CS, Molenaar JJ, Meerman J, Puigvert JC, Lamers F, Koster J, Danen EH, van de Water B, Versteeg R, Fitzsimons CP, Vreugdenhil E. Verissimo CS, et al. Among authors: molenaar jj. Endocr Relat Cancer. 2010 Apr 21;17(2):399-414. doi: 10.1677/ERC-09-0301. Print 2010 Jun. Endocr Relat Cancer. 2010. PMID: 20228126

8

A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients.

Fardin P, Barla A, Mosci S, Rosasco L, Verri A, Versteeg R, Caron HN, Molenaar JJ, Ora I, Eva A, Puppo M, Varesio L. Fardin P, et al. Among authors: molenaar jj. Mol Cancer. 2010 Jul 12;9:185. doi: 10.1186/1476-4598-9-185. Mol Cancer. 2010. PMID: 20624283 Free PMC article.

9

Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis.

Murphy DM, Buckley PG, Bryan K, Watters KM, Koster J, van Sluis P, Molenaar J, Versteeg R, Stallings RL. Murphy DM, et al. Mol Carcinog. 2011 Jun;50(6):403-11. doi: 10.1002/mc.20722. Epub 2010 Dec 28. Mol Carcinog. 2011. PMID: 21557326

10

Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe.

Lamers F, van der Ploeg I, Schild L, Ebus ME, Koster J, Hansen BR, Koch T, Versteeg R, Caron HN, Molenaar JJ. Lamers F, et al. Among authors: molenaar jj. Endocr Relat Cancer. 2011 Oct 27;18(6):657-68. doi: 10.1530/ERC-11-0207. Print 2011 Oct. Endocr Relat Cancer. 2011. PMID: 21859926

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