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DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks.
Mosbech A, Gibbs-Seymour I, Kagias K, Thorslund T, Beli P, Povlsen L, Nielsen SV, Smedegaard S, Sedgwick G, Lukas C, Hartmann-Petersen R, Lukas J, Choudhary C, Pocock R, Bekker-Jensen S, Mailand N. Mosbech A, et al. Nat Struct Mol Biol. 2012 Nov;19(11):1084-92. doi: 10.1038/nsmb.2395. Epub 2012 Oct 7. Nat Struct Mol Biol. 2012. PMID: 23042605
SLX4: not SIMply a nuclease scaffold?
Gibbs-Seymour I, Mailand N. Gibbs-Seymour I, et al. Mol Cell. 2015 Jan 8;57(1):3-5. doi: 10.1016/j.molcel.2014.12.032. Mol Cell. 2015. PMID: 25574947 Free article.
Serine-linked PARP1 auto-modification controls PARP inhibitor response.
Prokhorova E, Zobel F, Smith R, Zentout S, Gibbs-Seymour I, Schützenhofer K, Peters A, Groslambert J, Zorzini V, Agnew T, Brognard J, Nielsen ML, Ahel D, Huet S, Suskiewicz MJ, Ahel I. Prokhorova E, et al. Among authors: gibbs seymour i. Nat Commun. 2021 Jul 1;12(1):4055. doi: 10.1038/s41467-021-24361-9. Nat Commun. 2021. PMID: 34210965 Free PMC article.
MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response.
Staples CJ, Barone G, Myers KN, Ganesh A, Gibbs-Seymour I, Patil AA, Beveridge RD, Daye C, Beniston R, Maslen S, Ahel I, Skehel JM, Collis SJ. Staples CJ, et al. Among authors: gibbs seymour i. Cell Rep. 2016 Sep 6;16(10):2565-2575. doi: 10.1016/j.celrep.2016.07.087. Epub 2016 Aug 25. Cell Rep. 2016. PMID: 27568553 Free PMC article.
Serine ADP-Ribosylation Depends on HPF1.
Bonfiglio JJ, Fontana P, Zhang Q, Colby T, Gibbs-Seymour I, Atanassov I, Bartlett E, Zaja R, Ahel I, Matic I. Bonfiglio JJ, et al. Among authors: gibbs seymour i. Mol Cell. 2017 Mar 2;65(5):932-940.e6. doi: 10.1016/j.molcel.2017.01.003. Epub 2017 Feb 9. Mol Cell. 2017. PMID: 28190768 Free PMC article.
15 results