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A novel inhibitor of dengue virus replication that targets the capsid protein.
Byrd CM, Dai D, Grosenbach DW, Berhanu A, Jones KF, Cardwell KB, Schneider C, Wineinger KA, Page JM, Harver C, Stavale E, Tyavanagimatt S, Stone MA, Bartenschlager R, Scaturro P, Hruby DE, Jordan R. Byrd CM, et al. Among authors: bartenschlager r. Antimicrob Agents Chemother. 2013 Jan;57(1):15-25. doi: 10.1128/AAC.01429-12. Epub 2012 Oct 15. Antimicrob Agents Chemother. 2013. PMID: 23070172 Free PMC article.
Novel dengue virus NS2B/NS3 protease inhibitors.
Wu H, Bock S, Snitko M, Berger T, Weidner T, Holloway S, Kanitz M, Diederich WE, Steuber H, Walter C, Hofmann D, Weißbrich B, Spannaus R, Acosta EG, Bartenschlager R, Engels B, Schirmeister T, Bodem J. Wu H, et al. Among authors: bartenschlager r. Antimicrob Agents Chemother. 2015 Feb;59(2):1100-9. doi: 10.1128/AAC.03543-14. Epub 2014 Dec 8. Antimicrob Agents Chemother. 2015. PMID: 25487800 Free PMC article.
Dengue Virus Perturbs Mitochondrial Morphodynamics to Dampen Innate Immune Responses.
Chatel-Chaix L, Cortese M, Romero-Brey I, Bender S, Neufeldt CJ, Fischl W, Scaturro P, Schieber N, Schwab Y, Fischer B, Ruggieri A, Bartenschlager R. Chatel-Chaix L, et al. Among authors: bartenschlager r. Cell Host Microbe. 2016 Sep 14;20(3):342-356. doi: 10.1016/j.chom.2016.07.008. Epub 2016 Aug 18. Cell Host Microbe. 2016. PMID: 27545046 Free PMC article.
A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle.
Płaszczyca A, Scaturro P, Neufeldt CJ, Cortese M, Cerikan B, Ferla S, Brancale A, Pichlmair A, Bartenschlager R. Płaszczyca A, et al. Among authors: bartenschlager r. PLoS Pathog. 2019 May 9;15(5):e1007736. doi: 10.1371/journal.ppat.1007736. eCollection 2019 May. PLoS Pathog. 2019. PMID: 31071189 Free PMC article.
Determinants in Nonstructural Protein 4A of Dengue Virus Required for RNA Replication and Replication Organelle Biogenesis.
Cortese M, Mulder K, Chatel-Chaix L, Scaturro P, Cerikan B, Plaszczyca A, Haselmann U, Bartenschlager M, Neufeldt CJ, Bartenschlager R. Cortese M, et al. Among authors: bartenschlager m, bartenschlager r. J Virol. 2021 Oct 13;95(21):e0131021. doi: 10.1128/JVI.01310-21. Epub 2021 Aug 11. J Virol. 2021. PMID: 34379504 Free PMC article.
437 results