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Hydroxyurea responsiveness in β-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity.
Pourfarzad F, von Lindern M, Azarkeivan A, Hou J, Kia SK, Esteghamat F, van Ijcken W, Philipsen S, Najmabadi H, Grosveld F. Pourfarzad F, et al. Among authors: von lindern m. Haematologica. 2013 May;98(5):696-704. doi: 10.3324/haematol.2012.074492. Epub 2012 Oct 25. Haematologica. 2013. PMID: 23100274 Free PMC article.
Dynamic regulation of Gata factor levels is more important than their identity.
Ferreira R, Wai A, Shimizu R, Gillemans N, Rottier R, von Lindern M, Ohneda K, Grosveld F, Yamamoto M, Philipsen S. Ferreira R, et al. Among authors: von lindern m. Blood. 2007 Jun 15;109(12):5481-90. doi: 10.1182/blood-2006-11-060491. Epub 2007 Feb 27. Blood. 2007. PMID: 17327407 Free article.
Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin.
Borg J, Papadopoulos P, Georgitsi M, Gutiérrez L, Grech G, Fanis P, Phylactides M, Verkerk AJ, van der Spek PJ, Scerri CA, Cassar W, Galdies R, van Ijcken W, Ozgür Z, Gillemans N, Hou J, Bugeja M, Grosveld FG, von Lindern M, Felice AE, Patrinos GP, Philipsen S. Borg J, et al. Among authors: von lindern m. Nat Genet. 2010 Sep;42(9):801-5. doi: 10.1038/ng.630. Epub 2010 Aug 1. Nat Genet. 2010. PMID: 20676099 Free PMC article.
Fetal globin expression is regulated by Friend of Prmt1.
van Dijk TB, Gillemans N, Pourfarzad F, van Lom K, von Lindern M, Grosveld F, Philipsen S. van Dijk TB, et al. Among authors: von lindern m. Blood. 2010 Nov 18;116(20):4349-52. doi: 10.1182/blood-2010-03-274399. Epub 2010 Aug 5. Blood. 2010. PMID: 20688955 Free PMC article.
120 results