Aly A - Search Results

1

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.

Jaspers JE, Kersbergen A, Boon U, Sol W, van Deemter L, Zander SA, Drost R, Wientjens E, Ji J, Aly A, Doroshow JH, Cranston A, Martin NM, Lau A, O'Connor MJ, Ganesan S, Borst P, Jonkers J, Rottenberg S. Jaspers JE, et al. Among authors: aly a. Cancer Discov. 2013 Jan;3(1):68-81. doi: 10.1158/2159-8290.CD-12-0049. Epub 2012 Oct 25. Cancer Discov. 2013. PMID: 23103855 Free PMC article.

2

BRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability.

Aly A, Ganesan S. Aly A, et al. J Mol Cell Biol. 2011 Feb;3(1):66-74. doi: 10.1093/jmcb/mjq055. J Mol Cell Biol. 2011. PMID: 21278454 Free PMC article. Review.

3

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.

Bouwman P, Aly A, Escandell JM, Pieterse M, Bartkova J, van der Gulden H, Hiddingh S, Thanasoula M, Kulkarni A, Yang Q, Haffty BG, Tommiska J, Blomqvist C, Drapkin R, Adams DJ, Nevanlinna H, Bartek J, Tarsounas M, Ganesan S, Jonkers J. Bouwman P, et al. Among authors: aly a. Nat Struct Mol Biol. 2010 Jun;17(6):688-95. doi: 10.1038/nsmb.1831. Epub 2010 May 9. Nat Struct Mol Biol. 2010. PMID: 20453858 Free PMC article.

4

Low p53 binding protein 1 (53BP1) expression is associated with increased local recurrence in breast cancer patients treated with breast-conserving surgery and radiotherapy.

Neboori HJ, Haffty BG, Wu H, Yang Q, Aly A, Goyal S, Schiff D, Moran MS, Golhar R, Chen C, Moore D, Ganesan S. Neboori HJ, et al. Among authors: aly a. Int J Radiat Oncol Biol Phys. 2012 Aug 1;83(5):e677-83. doi: 10.1016/j.ijrobp.2012.01.089. Epub 2012 Apr 18. Int J Radiat Oncol Biol Phys. 2012. PMID: 22520477

5

Bioactive metabolites from Chaetomium aureum: structure elucidation and inhibition of the Hsp90 machine chaperoning activity.

Kabbaj FZ, Lu S, Faouzi Mel A, Meddah B, Proksch P, Cherrah Y, Altenbach HJ, Aly AH, Chadli A, Debbab A. Kabbaj FZ, et al. Among authors: aly ah. Bioorg Med Chem. 2015 Jan 1;23(1):126-31. doi: 10.1016/j.bmc.2014.11.021. Epub 2014 Nov 20. Bioorg Med Chem. 2015. PMID: 25482429 Free PMC article.

6

NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorum.

Aly AH, Debbab A, Clements C, Edrada-Ebel R, Orlikova B, Diederich M, Wray V, Lin W, Proksch P. Aly AH, et al. Bioorg Med Chem. 2011 Jan 1;19(1):414-21. doi: 10.1016/j.bmc.2010.11.012. Epub 2010 Nov 17. Bioorg Med Chem. 2011. PMID: 21146414

7

Embellicines A and B: absolute configuration and NF-κB transcriptional inhibitory activity.

Ebrahim W, Aly AH, Wray V, Mándi A, Teiten MH, Gaascht F, Orlikova B, Kassack MU, Lin W, Diederich M, Kurtán T, Debbab A, Proksch P. Ebrahim W, et al. Among authors: aly ah. J Med Chem. 2013 Apr 11;56(7):2991-9. doi: 10.1021/jm400034b. Epub 2013 Mar 29. J Med Chem. 2013. PMID: 23484593

8

A new tetrahydrofuran derivative from the endophytic fungus Chaetomium sp. isolated from Otanthus maritimus.

Aly AH, Debbab A, Edrada-Ebel R, Wray V, Müller WE, Lin W, Ebel R, Proksch P. Aly AH, et al. Z Naturforsch C J Biosci. 2009 May-Jun;64(5-6):350-4. doi: 10.1515/znc-2009-5-608. Z Naturforsch C J Biosci. 2009. PMID: 19678537 Free article.

9

Atropisomeric dihydroanthracenones as inhibitors of multiresistant Staphylococcus aureus.

Bara R, Zerfass I, Aly AH, Goldbach-Gecke H, Raghavan V, Sass P, Mándi A, Wray V, Polavarapu PL, Pretsch A, Lin W, Kurtán T, Debbab A, Brötz-Oesterhelt H, Proksch P. Bara R, et al. Among authors: aly ah. J Med Chem. 2013 Apr 25;56(8):3257-72. doi: 10.1021/jm301816a. Epub 2013 Apr 16. J Med Chem. 2013. PMID: 23534483

10

Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity.

Teiten MH, Mack F, Debbab A, Aly AH, Dicato M, Proksch P, Diederich M. Teiten MH, et al. Among authors: aly ah. Bioorg Med Chem. 2013 Jul 1;21(13):3850-8. doi: 10.1016/j.bmc.2013.04.024. Epub 2013 Apr 22. Bioorg Med Chem. 2013. PMID: 23664494

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