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Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor.
Barber LJ, Sandhu S, Chen L, Campbell J, Kozarewa I, Fenwick K, Assiotis I, Rodrigues DN, Reis Filho JS, Moreno V, Mateo J, Molife LR, De Bono J, Kaye S, Lord CJ, Ashworth A. Barber LJ, et al. Among authors: ashworth a. J Pathol. 2013 Feb;229(3):422-9. doi: 10.1002/path.4140. J Pathol. 2013. PMID: 23165508
Functions of the BRCA1 and BRCA2 genes.
Bertwistle D, Ashworth A. Bertwistle D, et al. Among authors: ashworth a. Curr Opin Genet Dev. 1998 Feb;8(1):14-20. doi: 10.1016/s0959-437x(98)80056-7. Curr Opin Genet Dev. 1998. PMID: 9529600 Review.
BRCA1 and BRCA2.
Bertwistle D, Ashworth A. Bertwistle D, et al. Among authors: ashworth a. Curr Biol. 2000 Aug 24;10(16):R582. doi: 10.1016/s0960-9822(00)00646-1. Curr Biol. 2000. PMID: 10985371 Free article. No abstract available.
New complexities for BRCA1 and BRCA2.
Kerr P, Ashworth A. Kerr P, et al. Among authors: ashworth a. Curr Biol. 2001 Aug 21;11(16):R668-76. doi: 10.1016/s0960-9822(01)00389-x. Curr Biol. 2001. PMID: 11525763 Free article. Review.
Phenotypic effects of heterozygosity for a BRCA2 mutation.
Warren M, Lord CJ, Masabanda J, Griffin D, Ashworth A. Warren M, et al. Among authors: ashworth a. Hum Mol Genet. 2003 Oct 15;12(20):2645-56. doi: 10.1093/hmg/ddg277. Epub 2003 Aug 19. Hum Mol Genet. 2003. PMID: 12928478
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Among authors: ashworth a. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967 Free article.
BRCA1 and BRCA2 as ovarian cancer susceptibility genes.
Sowter HM, Ashworth A. Sowter HM, et al. Among authors: ashworth a. Carcinogenesis. 2005 Oct;26(10):1651-6. doi: 10.1093/carcin/bgi136. Epub 2005 May 25. Carcinogenesis. 2005. PMID: 15917310
Targeting the DNA repair defect of BRCA tumours.
Turner N, Tutt A, Ashworth A. Turner N, et al. Among authors: ashworth a. Curr Opin Pharmacol. 2005 Aug;5(4):388-93. doi: 10.1016/j.coph.2005.03.006. Curr Opin Pharmacol. 2005. PMID: 15955736 Review.
825 results