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Identification of lineage-uncommitted, long-lived, label-retaining cells in healthy human esophagus and stomach, and in metaplastic esophagus.
Pan Q, Nicholson AM, Barr H, Harrison LA, Wilson GD, Burkert J, Jeffery R, Alison MR, Looijenga L, Lin WR, McDonald SA, Wright NA, Harrison R, Peppelenbosch MP, Jankowski JA. Pan Q, et al. Among authors: harrison r, harrison la. Gastroenterology. 2013 Apr;144(4):761-70. doi: 10.1053/j.gastro.2012.12.022. Epub 2012 Dec 22. Gastroenterology. 2013. PMID: 23266557 Free article.
Esophageal adenocarcinoma in "mice and men": back to basics!
Attwood SE, Harrison LA, Preston SL, Jankowski JA. Attwood SE, et al. Among authors: harrison la. Am J Gastroenterol. 2008 Sep;103(9):2367-72. doi: 10.1111/j.1572-0241.2008.02004.x. Am J Gastroenterol. 2008. PMID: 18844624 Review.
Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo.
Milicic A, Harrison LA, Goodlad RA, Hardy RG, Nicholson AM, Presz M, Sieber O, Santander S, Pringle JH, Mandir N, East P, Obszynska J, Sanders S, Piazuelo E, Shaw J, Harrison R, Tomlinson IP, McDonald SA, Wright NA, Jankowski JA. Milicic A, et al. Among authors: harrison r, harrison la. Cancer Res. 2008 Oct 1;68(19):7760-8. doi: 10.1158/0008-5472.CAN-08-0020. Cancer Res. 2008. PMID: 18829530 Free PMC article.
Role of MCD and Mössbauer Spectroscopy in the Explanation of the Properties of a Highly Soluble (μ-Oxo)bis[tetra(tert-butyl)(phthalocyaninato)iron(III)] Complex, Its Pyridine Adduct, and Redox Forms Oxidized under Anaerobic Conditions in Non-Coordinating Solvents.
Nemykin VN, Schrage BR, Nevonen DE, Harrison LA, Newman KME, Paidi VK, Lierop JV. Nemykin VN, et al. Among authors: harrison la. Inorg Chem. 2023 Jul 3;62(26):10203-10220. doi: 10.1021/acs.inorgchem.3c00897. Epub 2023 Jun 22. Inorg Chem. 2023. PMID: 37348114
Resolving a Half-Century-Long Controversy between (Magneto)optical and EPR Spectra of Single-Electron-Reduced [PcFe]-, [PcFeL]-, and [PcFeX]2- Complexes: Story of a Double Flip.
Schrage BR, Zhou W, Harrison LA, Nevonen DE, Thompson JR, Prosser KE, Walsby CJ, Ziegler CJ, Leznoff DB, Nemykin VN. Schrage BR, et al. Among authors: harrison la. Inorg Chem. 2022 Dec 19;61(50):20177-20199. doi: 10.1021/acs.inorgchem.2c03456. Epub 2022 Dec 6. Inorg Chem. 2022. PMID: 36472380
Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140.
Ghiboub M, Koster J, Craggs PD, Li Yim AYF, Shillings A, Hutchinson S, Bingham RP, Gatfield K, Hageman IL, Yao G, O'Keefe HP, Coffin A, Patel A, Sloan LA, Mitchell DJ, Hayhow TG, Lunven L, Watson RJ, Blunt CE, Harrison LA, Bruton G, Kumar U, Hamer N, Spaull JR, Zwijnenburg DA, Welting O, Hakvoort TBM, Te Velde AA, van Limbergen J, Henneman P, Prinjha RK, de Winther MPJ, Harker NR, Tough DF, de Jonge WJ. Ghiboub M, et al. Among authors: harrison la. BMC Biol. 2022 Aug 19;20(1):182. doi: 10.1186/s12915-022-01380-6. BMC Biol. 2022. PMID: 35986286 Free PMC article.
Design, Synthesis, and Characterization of I-BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate.
Humphreys PG, Atkinson SJ, Bamborough P, Bit RA, Chung CW, Craggs PD, Cutler L, Davis R, Ferrie A, Gong G, Gordon LJ, Gray M, Harrison LA, Hayhow TG, Haynes A, Henley N, Hirst DJ, Holyer ID, Lindon MJ, Lovatt C, Lugo D, McCleary S, Molnar J, Osmani Q, Patten C, Preston A, Rioja I, Seal JT, Smithers N, Sun F, Tang D, Taylor S, Theodoulou NH, Thomas C, Watson RJ, Wellaway CR, Zhu L, Tomkinson NCO, Prinjha RK. Humphreys PG, et al. Among authors: harrison la. J Med Chem. 2022 Feb 10;65(3):2262-2287. doi: 10.1021/acs.jmedchem.1c01747. Epub 2022 Jan 7. J Med Chem. 2022. PMID: 34995458 Free article.
Fragment-based Scaffold Hopping: Identification of Potent, Selective, and Highly Soluble Bromo and Extra Terminal Domain (BET) Second Bromodomain (BD2) Inhibitors.
Seal JT, Atkinson SJ, Bamborough P, Bassil A, Chung CW, Foley J, Gordon L, Grandi P, Gray JRJ, Harrison LA, Kruger RG, Matteo JJ, McCabe MT, Messenger C, Mitchell D, Phillipou A, Preston A, Prinjha RK, Rianjongdee F, Rioja I, Taylor S, Wall ID, Watson RJ, Woolven JM, Wyce A, Zhang XP, Demont EH. Seal JT, et al. Among authors: harrison la. J Med Chem. 2021 Aug 12;64(15):10772-10805. doi: 10.1021/acs.jmedchem.1c00365. Epub 2021 Jul 13. J Med Chem. 2021. PMID: 34255512
61 results