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DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge.
Patel V, Jalah R, Kulkarni V, Valentin A, Rosati M, Alicea C, von Gegerfelt A, Huang W, Guan Y, Keele BF, Bess JW Jr, Piatak M Jr, Lifson JD, Williams WT, Shen X, Tomaras GD, Amara RR, Robinson HL, Johnson W, Broderick KE, Sardesai NY, Venzon DJ, Hirsch VM, Felber BK, Pavlakis GN. Patel V, et al. Among authors: sardesai ny. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2975-80. doi: 10.1073/pnas.1215393110. Epub 2013 Jan 28. Proc Natl Acad Sci U S A. 2013. PMID: 23359688 Free PMC article.
Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques.
Kulkarni V, Jalah R, Ganneru B, Bergamaschi C, Alicea C, von Gegerfelt A, Patel V, Zhang GM, Chowdhury B, Broderick KE, Sardesai NY, Valentin A, Rosati M, Felber BK, Pavlakis GN. Kulkarni V, et al. Among authors: sardesai ny. Vaccine. 2011 Sep 9;29(39):6742-54. doi: 10.1016/j.vaccine.2010.12.056. Epub 2010 Dec 30. Vaccine. 2011. PMID: 21195080 Free PMC article.
Enhanced control of pathogenic Simian immunodeficiency virus SIVmac239 replication in macaques immunized with an interleukin-12 plasmid and a DNA prime-viral vector boost vaccine regimen.
Winstone N, Wilson AJ, Morrow G, Boggiano C, Chiuchiolo MJ, Lopez M, Kemelman M, Ginsberg AA, Mullen K, Coleman JW, Wu CD, Narpala S, Ouellette I, Dean HJ, Lin F, Sardesai NY, Cassamasa H, McBride D, Felber BK, Pavlakis GN, Schultz A, Hudgens MG, King CR, Zamb TJ, Parks CL, McDermott AB. Winstone N, et al. Among authors: sardesai ny. J Virol. 2011 Sep;85(18):9578-87. doi: 10.1128/JVI.05060-11. Epub 2011 Jul 6. J Virol. 2011. PMID: 21734035 Free PMC article.
IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques.
Jalah R, Patel V, Kulkarni V, Rosati M, Alicea C, Ganneru B, von Gegerfelt A, Huang W, Guan Y, Broderick KE, Sardesai NY, LaBranche C, Montefiori DC, Pavlakis GN, Felber BK. Jalah R, et al. Among authors: sardesai ny. Hum Vaccin Immunother. 2012 Nov 1;8(11):1620-9. doi: 10.4161/hv.21407. Epub 2012 Aug 16. Hum Vaccin Immunother. 2012. PMID: 22894956 Free PMC article.
The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production.
Jalah R, Rosati M, Ganneru B, Pilkington GR, Valentin A, Kulkarni V, Bergamaschi C, Chowdhury B, Zhang GM, Beach RK, Alicea C, Broderick KE, Sardesai NY, Pavlakis GN, Felber BK. Jalah R, et al. Among authors: sardesai ny. J Biol Chem. 2013 Mar 1;288(9):6763-76. doi: 10.1074/jbc.M112.436675. Epub 2013 Jan 7. J Biol Chem. 2013. PMID: 23297419 Free PMC article.
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