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Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury.
Arslan F, Lai RC, Smeets MB, Akeroyd L, Choo A, Aguor EN, Timmers L, van Rijen HV, Doevendans PA, Pasterkamp G, Lim SK, de Kleijn DP. Arslan F, et al. Among authors: doevendans pa. Stem Cell Res. 2013 May;10(3):301-12. doi: 10.1016/j.scr.2013.01.002. Epub 2013 Jan 14. Stem Cell Res. 2013. PMID: 23399448 Free article.
Role of apoptosis in reperfusion injury.
Eefting F, Rensing B, Wigman J, Pannekoek WJ, Liu WM, Cramer MJ, Lips DJ, Doevendans PA. Eefting F, et al. Among authors: doevendans pa. Cardiovasc Res. 2004 Feb 15;61(3):414-26. doi: 10.1016/j.cardiores.2003.12.023. Cardiovasc Res. 2004. PMID: 14962473 Review.
EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant.
van Empel VP, Bertrand AT, van Oort RJ, van der Nagel R, Engelen M, van Rijen HV, Doevendans PA, Crijns HJ, Ackerman SL, Sluiter W, De Windt LJ. van Empel VP, et al. Among authors: doevendans pa. J Am Coll Cardiol. 2006 Aug 15;48(4):824-32. doi: 10.1016/j.jacc.2006.02.075. Epub 2006 Jul 25. J Am Coll Cardiol. 2006. PMID: 16904556 Free article.
Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction.
Timmers L, Sluijter JP, van Keulen JK, Hoefer IE, Nederhoff MG, Goumans MJ, Doevendans PA, van Echteld CJ, Joles JA, Quax PH, Piek JJ, Pasterkamp G, de Kleijn DP. Timmers L, et al. Among authors: doevendans pa. Circ Res. 2008 Feb 1;102(2):257-64. doi: 10.1161/CIRCRESAHA.107.158220. Epub 2007 Nov 15. Circ Res. 2008. PMID: 18007026
846 results