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The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Roberts I, Shakur H, Coats T, Hunt B, Balogun E, Barnetson L, Cook L, Kawahara T, Perel P, Prieto-Merino D, Ramos M, Cairns J, Guerriero C. Roberts I, et al. Health Technol Assess. 2013 Mar;17(10):1-79. doi: 10.3310/hta17100. Health Technol Assess. 2013. PMID: 23477634 Free PMC article. Clinical Trial.
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
CRASH-2 trial collaborators; Shakur H, Roberts I, Bautista R, Caballero J, Coats T, Dewan Y, El-Sayed H, Gogichaishvili T, Gupta S, Herrera J, Hunt B, Iribhogbe P, Izurieta M, Khamis H, Komolafe E, Marrero MA, Mejía-Mantilla J, Miranda J, Morales C, Olaomi O, Olldashi F, Perel P, Peto R, Ramana PV, Ravi RR, Yutthakasemsunt S. CRASH-2 trial collaborators, et al. Among authors: roberts i. Lancet. 2010 Jul 3;376(9734):23-32. doi: 10.1016/S0140-6736(10)60835-5. Epub 2010 Jun 14. Lancet. 2010. PMID: 20554319 Clinical Trial.
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
CRASH-2 collaborators; Roberts I, Shakur H, Afolabi A, Brohi K, Coats T, Dewan Y, Gando S, Guyatt G, Hunt BJ, Morales C, Perel P, Prieto-Merino D, Woolley T. CRASH-2 collaborators, et al. Among authors: roberts i. Lancet. 2011 Mar 26;377(9771):1096-101, 1101.e1-2. doi: 10.1016/S0140-6736(11)60278-X. Lancet. 2011. PMID: 21439633 Clinical Trial.
CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury--a nested randomised, placebo-controlled trial.
Perel P, Al-Shahi Salman R, Kawahara T, Morris Z, Prieto-Merino D, Roberts I, Sandercock P, Shakur H, Wardlaw J. Perel P, et al. Among authors: roberts i. Health Technol Assess. 2012;16(13):iii-xii, 1-54. doi: 10.3310/hta16130. Health Technol Assess. 2012. PMID: 22417901 Free article. Clinical Trial.
Development and validation of a prognostic model to predict death in patients with traumatic bleeding, and evaluation of the effect of tranexamic acid on mortality according to baseline risk: a secondary analysis of a randomised controlled trial.
Perel P, Prieto-Merino D, Shakur H, Roberts I. Perel P, et al. Among authors: roberts i. Health Technol Assess. 2013 Jun;17(24):1-45, v-vi. doi: 10.3310/hta17240. Health Technol Assess. 2013. PMID: 23782457 Free PMC article. Clinical Trial.
Extending evidence for the use of tranexamic acid from traumatic haemorrhage to other patients with major bleeding: do we need more than one haemorrhage protocol? The case of gastrointestinal bleeding.
Stanworth SJ, Manno D, Shakur H, Coats T, Edwards P, Gilmore I, Jairath V, Veitch A, Roberts I. Stanworth SJ, et al. Among authors: roberts i. Transfus Med. 2015 Jun;25(3):198-200. doi: 10.1111/tme.12215. Epub 2015 Jun 17. Transfus Med. 2015. PMID: 26084425 Review. No abstract available.
1,540 results