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Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, Frezza C, Bernard NJ, Kelly B, Foley NH, Zheng L, Gardet A, Tong Z, Jany SS, Corr SC, Haneklaus M, Caffrey BE, Pierce K, Walmsley S, Beasley FC, Cummins E, Nizet V, Whyte M, Taylor CT, Lin H, Masters SL, Gottlieb E, Kelly VP, Clish C, Auron PE, Xavier RJ, O'Neill LA. Tannahill GM, et al. Among authors: beasley fc. Nature. 2013 Apr 11;496(7444):238-42. doi: 10.1038/nature11986. Epub 2013 Mar 24. Nature. 2013. PMID: 23535595 Free PMC article.
Human monocytes undergo functional re-programming during sepsis mediated by hypoxia-inducible factor-1α.
Shalova IN, Lim JY, Chittezhath M, Zinkernagel AS, Beasley F, Hernández-Jiménez E, Toledano V, Cubillos-Zapata C, Rapisarda A, Chen J, Duan K, Yang H, Poidinger M, Melillo G, Nizet V, Arnalich F, López-Collazo E, Biswas SK. Shalova IN, et al. Immunity. 2015 Mar 17;42(3):484-98. doi: 10.1016/j.immuni.2015.02.001. Epub 2015 Mar 3. Immunity. 2015. PMID: 25746953 Free article.
Methicillin-resistant Staphylococcus aureus bacterial nitric-oxide synthase affects antibiotic sensitivity and skin abscess development.
van Sorge NM, Beasley FC, Gusarov I, Gonzalez DJ, von Köckritz-Blickwede M, Anik S, Borkowski AW, Dorrestein PC, Nudler E, Nizet V. van Sorge NM, et al. Among authors: beasley fc. J Biol Chem. 2013 Mar 1;288(9):6417-26. doi: 10.1074/jbc.M112.448738. Epub 2013 Jan 15. J Biol Chem. 2013. PMID: 23322784 Free PMC article.
Staphylococcus aureus fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia.
Torres VJ, Attia AS, Mason WJ, Hood MI, Corbin BD, Beasley FC, Anderson KL, Stauff DL, McDonald WH, Zimmerman LJ, Friedman DB, Heinrichs DE, Dunman PM, Skaar EP. Torres VJ, et al. Among authors: beasley fc. Infect Immun. 2010 Apr;78(4):1618-28. doi: 10.1128/IAI.01423-09. Epub 2010 Jan 25. Infect Immun. 2010. PMID: 20100857 Free PMC article.
20 results