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Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.
Olmez I, Love S, Xiao A, Manigat L, Randolph P, McKenna BD, Neal BP, Boroda S, Li M, Brenneman B, Abounader R, Floyd D, Lee J, Nakano I, Godlewski J, Bronisz A, Sulman EP, Mayo M, Gioeli D, Weber M, Harris TE, Purow B. Olmez I, et al. Among authors: harris te. Neuro Oncol. 2018 Jan 22;20(2):192-202. doi: 10.1093/neuonc/nox119. Neuro Oncol. 2018. PMID: 29048560 Free PMC article.
Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness.
Manigat LC, Granade ME, Taori S, Miller CA, Vass LR, Zhong XP, Harris TE, Purow BW. Manigat LC, et al. Among authors: harris te. Front Immunol. 2021 Nov 5;12:722469. doi: 10.3389/fimmu.2021.722469. eCollection 2021. Front Immunol. 2021. PMID: 34804012 Free PMC article.
The Ligand Binding Landscape of Diacylglycerol Kinases.
Franks CE, Campbell ST, Purow BW, Harris TE, Hsu KL. Franks CE, et al. Among authors: harris te. Cell Chem Biol. 2017 Jul 20;24(7):870-880.e5. doi: 10.1016/j.chembiol.2017.06.007. Epub 2017 Jul 14. Cell Chem Biol. 2017. PMID: 28712745 Free PMC article.
Deconstructing Lipid Kinase Inhibitors by Chemical Proteomics.
McCloud RL, Franks CE, Campbell ST, Purow BW, Harris TE, Hsu KL. McCloud RL, et al. Among authors: harris te. Biochemistry. 2018 Jan 16;57(2):231-236. doi: 10.1021/acs.biochem.7b00962. Epub 2017 Nov 22. Biochemistry. 2018. PMID: 29155586 Free PMC article.
Disabled homolog 2 controls macrophage phenotypic polarization and adipose tissue inflammation.
Adamson SE, Griffiths R, Moravec R, Senthivinayagam S, Montgomery G, Chen W, Han J, Sharma PR, Mullins GR, Gorski SA, Cooper JA, Kadl A, Enfield K, Braciale TJ, Harris TE, Leitinger N. Adamson SE, et al. Among authors: harris te. J Clin Invest. 2016 Apr 1;126(4):1311-22. doi: 10.1172/JCI79590. Epub 2016 Feb 29. J Clin Invest. 2016. PMID: 26927671 Free PMC article.
113 results