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Arylsulfonamide pyrimidines as VLA-4 antagonists.
Bioorg Med Chem Lett. 2013 May 15;23(10):3070-4. doi: 10.1016/j.bmcl.2013.03.010. Epub 2013 Mar 15.
Bioorg Med Chem Lett. 2013.
PMID: 23562062
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region.
Probst GD, Bowers S, Sealy JM, Stupi B, Dressen D, Jagodzinska BM, Aquino J, Gailunas A, Truong AP, Tso L, Xu YZ, Hom RK, John V, Tung JS, Pleiss MA, Tucker JA, Konradi AW, Sham HL, Jagodzinski J, Toth G, Brecht E, Yao N, Pan H, Lin M, Artis DR, Ruslim L, Bova MP, Sinha S, Yednock TA, Gauby S, Zmolek W, Quinn KP, Sauer JM.
Probst GD, et al. Among authors: stupi b.
Bioorg Med Chem Lett. 2010 Oct 15;20(20):6034-9. doi: 10.1016/j.bmcl.2010.08.070. Epub 2010 Aug 19.
Bioorg Med Chem Lett. 2010.
PMID: 20822903
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Rapid incorporation kinetics and improved fidelity of a novel class of 3'-OH unblocked reversible terminators.
Gardner AF, Wang J, Wu W, Karouby J, Li H, Stupi BP, Jack WE, Hersh MN, Metzker ML.
Gardner AF, et al. Among authors: stupi bp.
Nucleic Acids Res. 2012 Aug;40(15):7404-15. doi: 10.1093/nar/gks330. Epub 2012 May 8.
Nucleic Acids Res. 2012.
PMID: 22570423
Free PMC article.
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Stereochemistry of benzylic carbon substitution coupled with ring modification of 2-nitrobenzyl groups as key determinants for fast-cleaving reversible terminators.
Stupi BP, Li H, Wang J, Wu W, Morris SE, Litosh VA, Muniz J, Hersh MN, Metzker ML.
Stupi BP, et al.
Angew Chem Int Ed Engl. 2012 Feb 13;51(7):1724-7. doi: 10.1002/anie.201106516. Epub 2012 Jan 9.
Angew Chem Int Ed Engl. 2012.
PMID: 22231919
Free PMC article.
No abstract available.
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Improved nucleotide selectivity and termination of 3'-OH unblocked reversible terminators by molecular tuning of 2-nitrobenzyl alkylated HOMedU triphosphates.
Litosh VA, Wu W, Stupi BP, Wang J, Morris SE, Hersh MN, Metzker ML.
Litosh VA, et al. Among authors: stupi bp.
Nucleic Acids Res. 2011 Mar;39(6):e39. doi: 10.1093/nar/gkq1293. Epub 2011 Jan 11.
Nucleic Acids Res. 2011.
PMID: 21227920
Free PMC article.
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Termination of DNA synthesis by N6-alkylated, not 3'-O-alkylated, photocleavable 2'-deoxyadenosine triphosphates.
Wu W, Stupi BP, Litosh VA, Mansouri D, Farley D, Morris S, Metzker S, Metzker ML.
Wu W, et al. Among authors: stupi bp.
Nucleic Acids Res. 2007;35(19):6339-49. doi: 10.1093/nar/gkm689. Epub 2007 Sep 18.
Nucleic Acids Res. 2007.
PMID: 17881370
Free PMC article.
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