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Phase I pharmacokinetic and pharmacodynamic study of SJG-136, a novel DNA sequence selective minor groove cross-linking agent, in advanced solid tumors.
Puzanov I, Lee W, Chen AP, Calcutt MW, Hachey DL, Vermeulen WL, Spanswick VJ, Liao CY, Hartley JA, Berlin JD, Rothenberg ML. Puzanov I, et al. Among authors: calcutt mw. Clin Cancer Res. 2011 Jun 1;17(11):3794-802. doi: 10.1158/1078-0432.CCR-10-2056. Epub 2011 Feb 23. Clin Cancer Res. 2011. PMID: 21346148 Free PMC article. Clinical Trial.
A phase I trial of SJG-136 (NSC#694501) in advanced solid tumors.
Janjigian YY, Lee W, Kris MG, Miller VA, Krug LM, Azzoli CG, Senturk E, Calcutt MW, Rizvi NA. Janjigian YY, et al. Among authors: calcutt mw. Cancer Chemother Pharmacol. 2010 Apr;65(5):833-8. doi: 10.1007/s00280-009-1088-4. Epub 2009 Aug 12. Cancer Chemother Pharmacol. 2010. PMID: 19672598 Free PMC article. Clinical Trial.
Hypusination Orchestrates the Antimicrobial Response of Macrophages.
Gobert AP, Finley JL, Latour YL, Asim M, Smith TM, Verriere TG, Barry DP, Allaman MM, Delagado AG, Rose KL, Calcutt MW, Schey KL, Sierra JC, Piazuelo MB, Mirmira RG, Wilson KT. Gobert AP, et al. Among authors: calcutt mw. Cell Rep. 2020 Dec 15;33(11):108510. doi: 10.1016/j.celrep.2020.108510. Cell Rep. 2020. PMID: 33326776 Free PMC article.
Cystathionine γ-lyase exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation.
Latour YL, Sierra JC, Finley JL, Asim M, Barry DP, Allaman MM, Smith TM, McNamara KM, Luis PB, Schneider C, Jacobse J, Goettel JA, Calcutt MW, Rose KL, Schey KL, Milne GL, Delgado AG, Piazuelo MB, Paul BD, Snyder SH, Gobert AP, Wilson KT. Latour YL, et al. Among authors: calcutt mw. JCI Insight. 2022 Jun 22;7(12):e155338. doi: 10.1172/jci.insight.155338. JCI Insight. 2022. PMID: 35579952 Free PMC article.
54 results