Wehner N - Search Results

1

Orally available and efficacious α4β1/α4β7 integrin inhibitors.

Xu YZ, Smith JL, Semko CM, Rossiter KI, Fukuda JY, Dappen MS, Quincy DA, Konradi AW, Mao W, Welch B, Dreyer ML, Samant B, Zhang H, Lugar J, Liao Z, Henschel C, Petersen E, Vandevert C, Shoemaker M, Wehner N, Mutter L, Shopp G, Krimm M, Chen L, Wipke B, Dofiles L, Gallager I, Sauer JM, Messersmith EK, Pleiss MA, Bard F, Yednock TA. Xu YZ, et al. Among authors: wehner n. Bioorg Med Chem Lett. 2013 Aug 1;23(15):4370-3. doi: 10.1016/j.bmcl.2013.05.076. Epub 2013 May 31. Bioorg Med Chem Lett. 2013. PMID: 23777782

2

Effects of natalizumab, an alpha4 integrin inhibitor, on the development of Hartley guinea pigs.

Wehner NG, Shopp G, Rocca MS, Clarke J. Wehner NG, et al. Birth Defects Res B Dev Reprod Toxicol. 2009 Apr;86(2):98-107. doi: 10.1002/bdrb.20189. Birth Defects Res B Dev Reprod Toxicol. 2009. PMID: 19294679

3

Embryo/fetal development in cynomolgus monkeys exposed to natalizumab, an alpha4 integrin inhibitor.

Wehner NG, Shopp G, Oneda S, Clarke J. Wehner NG, et al. Birth Defects Res B Dev Reprod Toxicol. 2009 Apr;86(2):117-30. doi: 10.1002/bdrb.20190. Birth Defects Res B Dev Reprod Toxicol. 2009. PMID: 19278014

4

Postnatal development in cynomolgus monkeys following prenatal exposure to natalizumab, an alpha4 integrin inhibitor.

Wehner NG, Shopp G, Osterburg I, Fuchs A, Buse E, Clarke J. Wehner NG, et al. Birth Defects Res B Dev Reprod Toxicol. 2009 Apr;86(2):144-56. doi: 10.1002/bdrb.20193. Birth Defects Res B Dev Reprod Toxicol. 2009. PMID: 19283860

5

Effects of natalizumab, an alpha4 integrin inhibitor, on fertility in male and female guinea pigs.

Wehner NG, Skov M, Shopp G, Rocca MS, Clarke J. Wehner NG, et al. Birth Defects Res B Dev Reprod Toxicol. 2009 Apr;86(2):108-16. doi: 10.1002/bdrb.20191. Birth Defects Res B Dev Reprod Toxicol. 2009. PMID: 19283862

6

Immunotoxicity profile of natalizumab.

Wehner NG, Gasper C, Shopp G, Nelson J, Draper K, Parker S, Clarke J. Wehner NG, et al. J Immunotoxicol. 2009 Jun;6(2):115-29. doi: 10.1080/15476910902977381. J Immunotoxicol. 2009. PMID: 19589098

7

Prevention and reduction of AD-type pathology in PDAPP mice immunized with A beta 1-42.

Games D, Bard F, Grajeda H, Guido T, Khan K, Soriano F, Vasquez N, Wehner N, Johnson-Wood K, Yednock T, Seubert P, Schenk D. Games D, et al. Among authors: wehner n. Ann N Y Acad Sci. 2000;920:274-84. doi: 10.1111/j.1749-6632.2000.tb06936.x. Ann N Y Acad Sci. 2000. PMID: 11193164

8

Development and validation of immunoassays to quantify the half-antibody exchange of an IgG4 antibody, natalizumab (Tysabri®) with endogenous IgG4.

Shapiro RI, Plavina T, Schlain BR, Pepinsky RB, Garber EA, Jarpe M, Hochman PS, Wehner NG, Bard F, Motter R, Yednock TA, Taylor FR. Shapiro RI, et al. Among authors: wehner ng. J Pharm Biomed Anal. 2011 Apr 28;55(1):168-75. doi: 10.1016/j.jpba.2011.01.006. Epub 2011 Jan 19. J Pharm Biomed Anal. 2011. PMID: 21300512

9

The guinea pig as an animal model for developmental and reproductive toxicology studies.

Rocca MS, Wehner NG. Rocca MS, et al. Among authors: wehner ng. Birth Defects Res B Dev Reprod Toxicol. 2009 Apr;86(2):92-7. doi: 10.1002/bdrb.20188. Birth Defects Res B Dev Reprod Toxicol. 2009. PMID: 19306306

10

Ultrasensitive radioimmunoassay of prostate-specific antigen.

Graves HC, Wehner N, Stamey TA. Graves HC, et al. Among authors: wehner n. Clin Chem. 1992 May;38(5):735-42. Clin Chem. 1992. PMID: 1374691

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