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The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants.
van Gisbergen KP, Klarenbeek PL, Kragten NA, Unger PP, Nieuwenhuis MB, Wensveen FM, ten Brinke A, Tak PP, Eldering E, Nolte MA, van Lier RA. van Gisbergen KP, et al. Among authors: ten brinke a. Immunity. 2011 Jul 22;35(1):97-108. doi: 10.1016/j.immuni.2011.04.020. Epub 2011 Jul 14. Immunity. 2011. PMID: 21763160 Free article.
A central role for Notch in effector CD8(+) T cell differentiation.
Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF, ten Brinke A, Willemsen AM, van Kampen AH, Kaech SM, Blander JM, van Gisbergen K, Amsen D. Backer RA, et al. Among authors: ten brinke a. Nat Immunol. 2014 Dec;15(12):1143-51. doi: 10.1038/ni.3027. Epub 2014 Oct 26. Nat Immunol. 2014. PMID: 25344724 Free PMC article.
Eomes broadens the scope of CD8 T-cell memory by inhibiting apoptosis in cells of low affinity.
Kavazović I, Han H, Balzaretti G, Slinger E, Lemmermann NAW, Ten Brinke A, Merkler D, Koster J, Bryceson YT, de Vries N, Jonjić S, Klarenbeek PL, Polić B, Eldering E, Wensveen FM. Kavazović I, et al. Among authors: ten brinke a. PLoS Biol. 2020 Mar 17;18(3):e3000648. doi: 10.1371/journal.pbio.3000648. eCollection 2020 Mar. PLoS Biol. 2020. PMID: 32182234 Free PMC article.
Clonal evolution of CD8+ T cell responses against latent viruses: relationship among phenotype, localization, and function.
Remmerswaal EB, Klarenbeek PL, Alves NL, Doorenspleet ME, van Schaik BD, Esveldt RE, Idu MM, van Leeuwen EM, van der Bom-Baylon N, van Kampen AH, Koch SD, Pircher H, Bemelman FJ, Ten Brinke A, Baas F, Ten Berge IJ, van Lier RA, de Vries N. Remmerswaal EB, et al. Among authors: ten berge ij, ten brinke a. J Virol. 2015 Jan;89(1):568-80. doi: 10.1128/JVI.02003-14. Epub 2014 Oct 22. J Virol. 2015. PMID: 25339770 Free PMC article.
184 results