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Page 1
Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial.
Alton EWFW, Armstrong DK, Ashby D, Bayfield KJ, Bilton D, Bloomfield EV, Boyd AC, Brand J, Buchan R, Calcedo R, Carvelli P, Chan M, Cheng SH, Collie DDS, Cunningham S, Davidson HE, Davies G, Davies JC, Davies LA, Dewar MH, Doherty A, Donovan J, Dwyer NS, Elgmati HI, Featherstone RF, Gavino J, Gea-Sorli S, Geddes DM, Gibson JSR, Gill DR, Greening AP, Griesenbach U, Hansell DM, Harman K, Higgins TE, Hodges SL, Hyde SC, Hyndman L, Innes JA, Jacob J, Jones N, Keogh BF, Limberis MP, Lloyd-Evans P, Maclean AW, Manvell MC, McCormick D, McGovern M, McLachlan G, Meng C, Montero MA, Milligan H, Moyce LJ, Murray GD, Nicholson AG, Osadolor T, Parra-Leiton J, Porteous DJ, Pringle IA, Punch EK, Pytel KM, Quittner AL, Rivellini G, Saunders CJ, Scheule RK, Sheard S, Simmonds NJ, Smith K, Smith SN, Soussi N, Soussi S, Spearing EJ, Stevenson BJ, Sumner-Jones SG, Turkkila M, Ureta RP, Waller MD, Wasowicz MY, Wilson JM, Wolstenholme-Hogg P; UK Cystic Fibrosis Gene Therapy Consortium. Alton EWFW, et al. Among authors: davies g, davies jc, davies la. Lancet Respir Med. 2015 Sep;3(9):684-691. doi: 10.1016/S2213-2600(15)00245-3. Epub 2015 Jul 3. Lancet Respir Med. 2015. PMID: 26149841 Free PMC article. Clinical Trial.
A Phase I/IIa Safety and Efficacy Study of Nebulized Liposome-mediated Gene Therapy for Cystic Fibrosis Supports a Multidose Trial.
Alton EW, Boyd AC, Porteous DJ, Davies G, Davies JC, Griesenbach U, Higgins TE, Gill DR, Hyde SC, Innes JA; UK Cystic Fibrosis Gene Therapy Consortium *. Alton EW, et al. Among authors: davies g, davies jc. Am J Respir Crit Care Med. 2015 Dec 1;192(11):1389-92. doi: 10.1164/rccm.201506-1193LE. Am J Respir Crit Care Med. 2015. PMID: 26623687 Free PMC article. Clinical Trial. No abstract available.
Pulmonary function deficits in newborn screened infants with cystic fibrosis managed with standard UK care are mild and transient.
Davies G, Stocks J, Thia LP, Hoo AF, Bush A, Aurora P, Brennan L, Lee S, Lum S, Cottam P, Miles J, Chudleigh J, Kirkby J, Balfour-Lynn IM, Carr SB, Wallis C, Wyatt H, Wade A; London Cystic Fibrosis Collaboration (LCFC). Davies G, et al. Eur Respir J. 2017 Nov 9;50(5):1700326. doi: 10.1183/13993003.00326-2017. Print 2017 Nov. Eur Respir J. 2017. PMID: 29122914 Free article.
Fair selection of participants in clinical trials: The challenge to push the envelope further.
Davies JC, Scott S, Dobra R, Brendell R, Brownlee K, Carr SB, Cosgriff R, Simmonds NJ; London Network of Clinical Trials Accelerator Platform sites; Jahan R, Jones A, Matthews J, Brown S, Galono K, Miles K, Pao C, Shafi N, Watson D, Orchard C, Davies G, Pike K, Shah S, Bossley CJ, Fong T, Macedo P, Ruiz G, Waller M, Baker L. Davies JC, et al. Among authors: davies g. J Cyst Fibros. 2019 Sep;18(5):e48-e50. doi: 10.1016/j.jcf.2019.07.004. Epub 2019 Aug 9. J Cyst Fibros. 2019. PMID: 31405729 Free article. No abstract available.
Minimal change in structural, functional and inflammatory markers of lung disease in newborn screened infants with cystic fibrosis at one year.
Davies G, Thia LP, Stocks J, Bush A, Hoo AF, Wade A, Nguyen TTD, Brody AS, Calder A, Klein NJ, Carr SB, Wallis C, Suri R, Pao CS, Ruiz G, Balfour-Lynn IM; London Cystic Fibrosis Collaboration (LCFC). Davies G, et al. J Cyst Fibros. 2020 Nov;19(6):896-901. doi: 10.1016/j.jcf.2020.01.006. Epub 2020 Feb 7. J Cyst Fibros. 2020. PMID: 32044244 Free article.
An observational study of the lung clearance index throughout childhood in cystic fibrosis: early years matter.
Davies G, Stanojevic S, Raywood E, Duncan JA, Stocks J, Lum S, Bush A, Viviani L, Wade A, Calder A, Owens CM, Goubau C, Carr SB, Bossley CJ, Pao C, Aurora P; London Cystic Fibrosis Collaboration. Davies G, et al. Eur Respir J. 2020 Oct 1;56(4):2000006. doi: 10.1183/13993003.00006-2020. Print 2020 Oct. Eur Respir J. 2020. PMID: 32444409 Free PMC article.
3,494 results