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CaMKII is essential for the proasthmatic effects of oxidation.
Sanders PN, Koval OM, Jaffer OA, Prasad AM, Businga TR, Scott JA, Hayden PJ, Luczak ED, Dickey DD, Allamargot C, Olivier AK, Meyerholz DK, Robison AJ, Winder DG, Blackwell TS, Dworski R, Sammut D, Wagner BA, Buettner GR, Pope RM, Miller FJ Jr, Dibbern ME, Haitchi HM, Mohler PJ, Howarth PH, Zabner J, Kline JN, Grumbach IM, Anderson ME. Sanders PN, et al. Among authors: prasad am. Sci Transl Med. 2013 Jul 24;5(195):195ra97. doi: 10.1126/scitranslmed.3006135. Sci Transl Med. 2013. PMID: 23884469 Free PMC article.
Oxidative activation of the Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) regulates vascular smooth muscle migration and apoptosis.
Zhu LJ, Klutho PJ, Scott JA, Xie L, Luczak ED, Dibbern ME, Prasad AM, Jaffer OA, Venema AN, Nguyen EK, Guan X, Anderson ME, Grumbach IM. Zhu LJ, et al. Among authors: prasad am. Vascul Pharmacol. 2014 Feb;60(2):75-83. doi: 10.1016/j.vph.2014.01.001. Epub 2014 Jan 10. Vascul Pharmacol. 2014. PMID: 24418021 Free PMC article.
The multifunctional Ca²⁺/calmodulin-dependent kinase IIδ (CaMKIIδ) regulates arteriogenesis in a mouse model of flow-mediated remodeling.
Scott JA, Klutho PJ, El Accaoui R, Nguyen E, Venema AN, Xie L, Jiang S, Dibbern M, Scroggins S, Prasad AM, Luczak ED, Davis MK, Li W, Guan X, Backs J, Schlueter AJ, Weiss RM, Miller FJ, Anderson ME, Grumbach IM. Scott JA, et al. Among authors: prasad am. PLoS One. 2013 Aug 8;8(8):e71550. doi: 10.1371/journal.pone.0071550. eCollection 2013. PLoS One. 2013. PMID: 23951185 Free PMC article.
Mitochondrial-targeted antioxidant therapy decreases transforming growth factor-β-mediated collagen production in a murine asthma model.
Jaffer OA, Carter AB, Sanders PN, Dibbern ME, Winters CJ, Murthy S, Ryan AJ, Rokita AG, Prasad AM, Zabner J, Kline JN, Grumbach IM, Anderson ME. Jaffer OA, et al. Among authors: prasad am. Am J Respir Cell Mol Biol. 2015 Jan;52(1):106-15. doi: 10.1165/rcmb.2013-0519OC. Am J Respir Cell Mol Biol. 2015. PMID: 24988374 Free PMC article.
Calcium/calmodulin-dependent kinase II inhibition in smooth muscle reduces angiotensin II-induced hypertension by controlling aortic remodeling and baroreceptor function.
Prasad AM, Morgan DA, Nuno DW, Ketsawatsomkron P, Bair TB, Venema AN, Dibbern ME, Kutschke WJ, Weiss RM, Lamping KG, Chapleau MW, Sigmund CD, Rahmouni K, Grumbach IM. Prasad AM, et al. J Am Heart Assoc. 2015 Jun 15;4(6):e001949. doi: 10.1161/JAHA.115.001949. J Am Heart Assoc. 2015. PMID: 26077587 Free PMC article.
Role of CaMKII in Ang-II-dependent small artery remodeling.
Prasad AM, Ketsawatsomkron P, Nuno DW, Koval OM, Dibbern ME, Venema AN, Sigmund CD, Lamping KG, Grumbach IM. Prasad AM, et al. Vascul Pharmacol. 2016 Dec;87:172-179. doi: 10.1016/j.vph.2016.09.007. Epub 2016 Sep 20. Vascul Pharmacol. 2016. PMID: 27658984 Free PMC article.
35 results