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Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.
Schlee M, Roth A, Hornung V, Hagmann CA, Wimmenauer V, Barchet W, Coch C, Janke M, Mihailovic A, Wardle G, Juranek S, Kato H, Kawai T, Poeck H, Fitzgerald KA, Takeuchi O, Akira S, Tuschl T, Latz E, Ludwig J, Hartmann G. Schlee M, et al. Among authors: hartmann g. Immunity. 2009 Jul 17;31(1):25-34. doi: 10.1016/j.immuni.2009.05.008. Epub 2009 Jul 2. Immunity. 2009. PMID: 19576794 Free PMC article.
SiRNA delivery with exosome nanoparticles.
van den Boorn JG, Schlee M, Coch C, Hartmann G. van den Boorn JG, et al. Among authors: hartmann g. Nat Biotechnol. 2011 Apr;29(4):325-6. doi: 10.1038/nbt.1830. Nat Biotechnol. 2011. PMID: 21478846 No abstract available.
Nucleic acid adjuvants: toward an educated vaccine.
van den Boorn JG, Barchet W, Hartmann G. van den Boorn JG, et al. Among authors: hartmann g. Adv Immunol. 2012;114:1-32. doi: 10.1016/B978-0-12-396548-6.00001-9. Adv Immunol. 2012. PMID: 22449776 Review.
Exosomes as nucleic acid nanocarriers.
van den Boorn JG, Dassler J, Coch C, Schlee M, Hartmann G. van den Boorn JG, et al. Among authors: hartmann g. Adv Drug Deliv Rev. 2013 Mar;65(3):331-5. doi: 10.1016/j.addr.2012.06.011. Epub 2012 Jun 28. Adv Drug Deliv Rev. 2013. PMID: 22750807 Review.
Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma.
Glas M, Coch C, Trageser D, Dassler J, Simon M, Koch P, Mertens J, Quandel T, Gorris R, Reinartz R, Wieland A, Von Lehe M, Pusch A, Roy K, Schlee M, Neumann H, Fimmers R, Herrlinger U, Brüstle O, Hartmann G, Besch R, Scheffler B. Glas M, et al. Among authors: hartmann g. Stem Cells. 2013 Jun;31(6):1064-74. doi: 10.1002/stem.1350. Stem Cells. 2013. PMID: 23390110
A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA.
Schuberth-Wagner C, Ludwig J, Bruder AK, Herzner AM, Zillinger T, Goldeck M, Schmidt T, Schmid-Burgk JL, Kerber R, Wolter S, Stümpel JP, Roth A, Bartok E, Drosten C, Coch C, Hornung V, Barchet W, Kümmerer BM, Hartmann G, Schlee M. Schuberth-Wagner C, et al. Among authors: hartmann g. Immunity. 2015 Jul 21;43(1):41-51. doi: 10.1016/j.immuni.2015.06.015. Epub 2015 Jul 14. Immunity. 2015. PMID: 26187414 Free PMC article.
Inflammasome-Dependent Induction of Adaptive NK Cell Memory.
van den Boorn JG, Jakobs C, Hagen C, Renn M, Luiten RM, Melief CJ, Tüting T, Garbi N, Hartmann G, Hornung V. van den Boorn JG, et al. Among authors: hartmann g. Immunity. 2016 Jun 21;44(6):1406-21. doi: 10.1016/j.immuni.2016.05.008. Epub 2016 Jun 7. Immunity. 2016. PMID: 27287410 Free article.
788 results