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The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Sonati T, Reimann RR, Falsig J, Baral PK, O'Connor T, Hornemann S, Yaganoglu S, Li B, Herrmann US, Wieland B, Swayampakula M, Rahman MH, Das D, Kav N, Riek R, Liberski PP, James MN, Aguzzi A. Sonati T, et al. Among authors: riek r. Nature. 2013 Sep 5;501(7465):102-6. doi: 10.1038/nature12402. Epub 2013 Jul 31. Nature. 2013. PMID: 23903654 Free article.
Prion (PrPSc)-specific epitope defined by a monoclonal antibody.
Korth C, Stierli B, Streit P, Moser M, Schaller O, Fischer R, Schulz-Schaeffer W, Kretzschmar H, Raeber A, Braun U, Ehrensperger F, Hornemann S, Glockshuber R, Riek R, Billeter M, Wüthrich K, Oesch B. Korth C, et al. Among authors: riek r. Nature. 1997 Nov 6;390(6655):74-7. doi: 10.1038/36337. Nature. 1997. PMID: 9363892
Prion protein NMR structure and species barrier for prion diseases.
Billeter M, Riek R, Wider G, Hornemann S, Glockshuber R, Wüthrich K. Billeter M, et al. Among authors: riek r. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7281-5. doi: 10.1073/pnas.94.14.7281. Proc Natl Acad Sci U S A. 1997. PMID: 9207082 Free PMC article.
Binding of Polythiophenes to Amyloids: Structural Mapping of the Pharmacophore.
Schütz AK, Hornemann S, Wälti MA, Greuter L, Tiberi C, Cadalbert R, Gantner M, Riek R, Hammarström P, Nilsson KPR, Böckmann A, Aguzzi A, Meier BH. Schütz AK, et al. Among authors: riek r. ACS Chem Neurosci. 2018 Mar 21;9(3):475-481. doi: 10.1021/acschemneuro.7b00397. Epub 2017 Dec 4. ACS Chem Neurosci. 2018. PMID: 29178774
258 results