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Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, Dong J, Dooley S, Drasdo D, Eakins R, Ferreira KS, Fonsato V, Fraczek J, Gebhardt R, Gibson A, Glanemann M, Goldring CE, Gómez-Lechón MJ, Groothuis GM, Gustavsson L, Guyot C, Hallifax D, Hammad S, Hayward A, Häussinger D, Hellerbrand C, Hewitt P, Hoehme S, Holzhütter HG, Houston JB, Hrach J, Ito K, Jaeschke H, Keitel V, Kelm JM, Kevin Park B, Kordes C, Kullak-Ublick GA, LeCluyse EL, Lu P, Luebke-Wheeler J, Lutz A, Maltman DJ, Matz-Soja M, McMullen P, Merfort I, Messner S, Meyer C, Mwinyi J, Naisbitt DJ, Nussler AK, Olinga P, Pampaloni F, Pi J, Pluta L, Przyborski SA, Ramachandran A, Rogiers V, Rowe C, Schelcher C, Schmich K, Schwarz M, Singh B, Stelzer EH, Stieger B, Stöber R, Sugiyama Y, Tetta C, Thasler WE, Vanhaecke T, Vinken M, Weiss TS, Widera A, Woods CG, Xu JJ, Yarborough KM, Hengstler JG. Godoy P, et al. Among authors: meyer c. Arch Toxicol. 2013 Aug;87(8):1315-530. doi: 10.1007/s00204-013-1078-5. Epub 2013 Aug 23. Arch Toxicol. 2013. PMID: 23974980 Free PMC article. Review.
TGF-beta signaling in alcohol induced hepatic injury.
Meyer C, Meindl-Beinker NM, Dooley S. Meyer C, et al. Front Biosci (Landmark Ed). 2010 Jan 1;15(2):740-9. doi: 10.2741/3643. Front Biosci (Landmark Ed). 2010. PMID: 20036843 Free article. Review.
Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes.
Zellmer S, Schmidt-Heck W, Godoy P, Weng H, Meyer C, Lehmann T, Sparna T, Schormann W, Hammad S, Kreutz C, Timmer J, von Weizsäcker F, Thürmann PA, Merfort I, Guthke R, Dooley S, Hengstler JG, Gebhardt R. Zellmer S, et al. Among authors: meyer c. Hepatology. 2010 Dec;52(6):2127-36. doi: 10.1002/hep.23930. Epub 2010 Oct 26. Hepatology. 2010. PMID: 20979052
Animal models of chronic liver diseases.
Liu Y, Meyer C, Xu C, Weng H, Hellerbrand C, ten Dijke P, Dooley S. Liu Y, et al. Among authors: meyer c. Am J Physiol Gastrointest Liver Physiol. 2013 Mar 1;304(5):G449-68. doi: 10.1152/ajpgi.00199.2012. Epub 2012 Dec 28. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23275613 Free article. Review.
Caveolin and TGF-β entanglements.
Meyer C, Liu Y, Dooley S. Meyer C, et al. J Cell Physiol. 2013 Nov;228(11):2097-102. doi: 10.1002/jcp.24380. J Cell Physiol. 2013. PMID: 23559144 Review.
Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis.
Hammad S, Hoehme S, Friebel A, von Recklinghausen I, Othman A, Begher-Tibbe B, Reif R, Godoy P, Johann T, Vartak A, Golka K, Bucur PO, Vibert E, Marchan R, Christ B, Dooley S, Meyer C, Ilkavets I, Dahmen U, Dirsch O, Böttger J, Gebhardt R, Drasdo D, Hengstler JG. Hammad S, et al. Among authors: meyer c. Arch Toxicol. 2014 May;88(5):1161-83. doi: 10.1007/s00204-014-1243-5. Epub 2014 Apr 19. Arch Toxicol. 2014. PMID: 24748404 Free PMC article.
5,378 results