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Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure.
Suddala KC, Rinaldi AJ, Feng J, Mustoe AM, Eichhorn CD, Liberman JA, Wedekind JE, Al-Hashimi HM, Brooks CL 3rd, Walter NG. Suddala KC, et al. Among authors: wedekind je. Nucleic Acids Res. 2013 Dec;41(22):10462-75. doi: 10.1093/nar/gkt798. Epub 2013 Sep 3. Nucleic Acids Res. 2013. PMID: 24003028 Free PMC article.
Riboswitch structure in the ligand-free state.
Liberman JA, Wedekind JE. Liberman JA, et al. Among authors: wedekind je. Wiley Interdiscip Rev RNA. 2012 May-Jun;3(3):369-84. doi: 10.1002/wrna.114. Epub 2011 Sep 28. Wiley Interdiscip Rev RNA. 2012. PMID: 21957061 Free PMC article. Review.
Crystallographic analysis of small ribozymes and riboswitches.
Lippa GM, Liberman JA, Jenkins JL, Krucinska J, Salim M, Wedekind JE. Lippa GM, et al. Among authors: wedekind je. Methods Mol Biol. 2012;848:159-84. doi: 10.1007/978-1-61779-545-9_11. Methods Mol Biol. 2012. PMID: 22315069 Free PMC article.
ITC analysis of ligand binding to preQ₁ riboswitches.
Liberman JA, Bogue JT, Jenkins JL, Salim M, Wedekind JE. Liberman JA, et al. Among authors: wedekind je. Methods Enzymol. 2014;549:435-50. doi: 10.1016/B978-0-12-801122-5.00018-0. Methods Enzymol. 2014. PMID: 25432759 Free PMC article.
Structural analysis of a class III preQ1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics.
Liberman JA, Suddala KC, Aytenfisu A, Chan D, Belashov IA, Salim M, Mathews DH, Spitale RC, Walter NG, Wedekind JE. Liberman JA, et al. Among authors: wedekind je. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3485-94. doi: 10.1073/pnas.1503955112. Epub 2015 Jun 23. Proc Natl Acad Sci U S A. 2015. PMID: 26106162 Free PMC article.
86 results