MacKenzie KL - Search Results

1

Modeling human endothelial cell transformation in vascular neoplasias.

Wen VW, MacKenzie KL. Wen VW, et al. Among authors: mackenzie kl. Dis Model Mech. 2013 Sep;6(5):1066-79. doi: 10.1242/dmm.012674. Dis Model Mech. 2013. PMID: 24046386 Free PMC article. Review.

2

Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization.

Kan CY, Wen VW, Pasquier E, Jankowski K, Chang M, Richards LA, Kavallaris M, MacKenzie KL. Kan CY, et al. Among authors: mackenzie kl. Oncogene. 2012 Nov 15;31(46):4815-27. doi: 10.1038/onc.2011.645. Epub 2012 Feb 6. Oncogene. 2012. PMID: 22310292 Free PMC article.

3

Telomere-driven karyotypic complexity concurs with p16INK4a inactivation in TP53-competent immortal endothelial cells.

Wen VW, Wu K, Baksh S, Hinshelwood RA, Lock RB, Clark SJ, Moore MA, Mackenzie KL. Wen VW, et al. Among authors: mackenzie kl. Cancer Res. 2006 Nov 15;66(22):10691-700. doi: 10.1158/0008-5472.CAN-06-0979. Cancer Res. 2006. PMID: 17108106

4

Targeting telomerase in hematologic malignancy.

Maritz MF, Napier CE, Wen VW, MacKenzie KL. Maritz MF, et al. Among authors: mackenzie kl. Future Oncol. 2010 May;6(5):769-89. doi: 10.2217/fon.10.42. Future Oncol. 2010. PMID: 20465390 Review.

5

Mild hyperoxia limits hTR levels, telomerase activity, and telomere length maintenance in hTERT-transduced bone marrow endothelial cells.

Napier CE, Veas LA, Kan CY, Taylor LM, Yuan J, Wen VW, James A, O'Brien TA, Lock RB, MacKenzie KL. Napier CE, et al. Among authors: mackenzie kl. Biochim Biophys Acta. 2010 Oct;1803(10):1142-53. doi: 10.1016/j.bbamcr.2010.06.010. Epub 2010 Jul 7. Biochim Biophys Acta. 2010. PMID: 20619302 Free article.

6

Over-expression of p53 mutants in LNCaP cells alters tumor growth and angiogenesis in vivo.

Perryman LA, Blair JM, Kingsley EA, Szymanska B, Ow KT, Wen VW, MacKenzie KL, Vermeulen PB, Jackson P, Russell PJ. Perryman LA, et al. Among authors: mackenzie kl. Biochem Biophys Res Commun. 2006 Jul 7;345(3):1207-14. doi: 10.1016/j.bbrc.2006.05.020. Epub 2006 May 11. Biochem Biophys Res Commun. 2006. PMID: 16723121

7

Induction of vascular endothelial growth factor secretion by childhood acute lymphoblastic leukemia cells via the FLT-3 signaling pathway.

Markovic A, MacKenzie KL, Lock RB. Markovic A, et al. Among authors: mackenzie kl. Mol Cancer Ther. 2012 Jan;11(1):183-93. doi: 10.1158/1535-7163.MCT-11-0503. Epub 2011 Nov 14. Mol Cancer Ther. 2012. PMID: 22084166

8

Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase.

Yuan J, Yang BM, Zhong ZH, Shats I, Milyavsky M, Rotter V, Lock RB, Reddel RR, MacKenzie KL. Yuan J, et al. Among authors: mackenzie kl. Oncogene. 2009 Jul 23;28(29):2678-89. doi: 10.1038/onc.2009.136. Epub 2009 Jun 1. Oncogene. 2009. PMID: 19483728

9

Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras.

MacKenzie KL, Franco S, Naiyer AJ, May C, Sadelain M, Rafii S, Moore MA. MacKenzie KL, et al. Oncogene. 2002 Jun 20;21(27):4200-11. doi: 10.1038/sj.onc.1205425. Oncogene. 2002. PMID: 12082607

10

Up-regulation of survivin during immortalization of human myofibroblasts is linked to repression of tumor suppressor p16(INK4a) protein and confers resistance to oxidative stress.

Kan CY, Petti C, Bracken L, Maritz M, Xu N, O'Brien R, Yang C, Liu T, Yuan J, Lock RB, MacKenzie KL. Kan CY, et al. Among authors: mackenzie kl. J Biol Chem. 2013 Apr 26;288(17):12032-41. doi: 10.1074/jbc.M112.447821. Epub 2013 Feb 28. J Biol Chem. 2013. PMID: 23449974 Free PMC article.

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