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Integrative annotation of variants from 1092 humans: application to cancer genomics.
Khurana E, Fu Y, Colonna V, Mu XJ, Kang HM, Lappalainen T, Sboner A, Lochovsky L, Chen J, Harmanci A, Das J, Abyzov A, Balasubramanian S, Beal K, Chakravarty D, Challis D, Chen Y, Clarke D, Clarke L, Cunningham F, Evani US, Flicek P, Fragoza R, Garrison E, Gibbs R, Gümüş ZH, Herrero J, Kitabayashi N, Kong Y, Lage K, Liluashvili V, Lipkin SM, MacArthur DG, Marth G, Muzny D, Pers TH, Ritchie GRS, Rosenfeld JA, Sisu C, Wei X, Wilson M, Xue Y, Yu F; 1000 Genomes Project Consortium; Dermitzakis ET, Yu H, Rubin MA, Tyler-Smith C, Gerstein M. Khurana E, et al. Among authors: gumus zh. Science. 2013 Oct 4;342(6154):1235587. doi: 10.1126/science.1235587. Science. 2013. PMID: 24092746 Free PMC article.
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1+ PD-1+ CD8 T cells.
Humblin E, Korpas I, Lu J, Filipescu D, van der Heide V, Goldstein S, Vaidya A, Soares-Schanoski A, Casati B, Selvan ME, Gümüş ZH, Wieland A, Corrado M, Cohen-Gould L, Bernstein E, Homann D, Chipuk J, Kamphorst AO. Humblin E, et al. Among authors: gumus zh. Sci Immunol. 2023 Aug 4;8(86):eadg0878. doi: 10.1126/sciimmunol.adg0878. Epub 2023 Aug 25. Sci Immunol. 2023. PMID: 37624910 Free PMC article.
miR-23a promotes the transition from indolent to invasive colorectal cancer.
Jahid S, Sun J, Edwards RA, Dizon D, Panarelli NC, Milsom JW, Sikandar SS, Gümüs ZH, Lipkin SM. Jahid S, et al. Among authors: gumus zh. Cancer Discov. 2012 Jun;2(6):540-53. doi: 10.1158/2159-8290.CD-11-0267. Epub 2012 Mar 30. Cancer Discov. 2012. PMID: 22628407 Free PMC article.
A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells.
Bu P, Chen KY, Chen JH, Wang L, Walters J, Shin YJ, Goerger JP, Sun J, Witherspoon M, Rakhilin N, Li J, Yang H, Milsom J, Lee S, Zipfel W, Jin MM, Gümüş ZH, Lipkin SM, Shen X. Bu P, et al. Among authors: gumus zh. Cell Stem Cell. 2013 May 2;12(5):602-15. doi: 10.1016/j.stem.2013.03.002. Cell Stem Cell. 2013. PMID: 23642368 Free PMC article.
miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β.
Bu P, Wang L, Chen KY, Rakhilin N, Sun J, Closa A, Tung KL, King S, Kristine Varanko A, Xu Y, Huan Chen J, Zessin AS, Shealy J, Cummings B, Hsu D, Lipkin SM, Moreno V, Gümüş ZH, Shen X. Bu P, et al. Among authors: gumus zh. Nat Commun. 2015 Apr 15;6:6879. doi: 10.1038/ncomms7879. Nat Commun. 2015. PMID: 25872451 Free PMC article.
64 results