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C3d-Targeted factor H inhibits tissue complement in disease models and reduces glomerular injury without affecting circulating complement.
Liu F, Ryan ST, Fahnoe KC, Morgan JG, Cheung AE, Storek MJ, Best A, Chen HA, Locatelli M, Xu S, Schmidt E, Schmidt-Jiménez LF, Bieber K, Henderson JM, Lian CG, Verschoor A, Ludwig RJ, Benigni A, Remuzzi G, Salant DJ, Kalled SL, Thurman JM, Holers VM, Violette SM, Wawersik S. Liu F, et al. Among authors: violette sm. Mol Ther. 2024 Apr 3;32(4):1061-1079. doi: 10.1016/j.ymthe.2024.02.001. Epub 2024 Feb 20. Mol Ther. 2024. PMID: 38382529 Free article.
A Phase IIb Randomized Clinical Study of an Anti-αvβ6 Monoclonal Antibody in Idiopathic Pulmonary Fibrosis.
Raghu G, Mouded M, Chambers DC, Martinez FJ, Richeldi L, Lancaster LH, Hamblin MJ, Gibson KF, Rosas IO, Prasse A, Zhao G, Serenko M, Novikov N, McCurley A, Bansal P, Stebbins C, Arefayene M, Ibebunjo S, Violette SM, Gallagher D, Behr J. Raghu G, et al. Among authors: violette sm. Am J Respir Crit Care Med. 2022 Nov 1;206(9):1128-1139. doi: 10.1164/rccm.202112-2824OC. Am J Respir Crit Care Med. 2022. PMID: 35771569 Clinical Trial.
The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis.
Krishn SR, Salem I, Quaglia F, Naranjo NM, Agarwal E, Liu Q, Sarker S, Kopenhaver J, McCue PA, Weinreb PH, Violette SM, Altieri DC, Languino LR. Krishn SR, et al. Among authors: violette sm. J Extracell Vesicles. 2020 May 20;9(1):1763594. doi: 10.1080/20013078.2020.1763594. eCollection 2020. J Extracell Vesicles. 2020. PMID: 32595914 Free PMC article.
Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis.
Shea BS, Probst CK, Brazee PL, Rotile NJ, Blasi F, Weinreb PH, Black KE, Sosnovik DE, Van Cott EM, Violette SM, Caravan P, Tager AM. Shea BS, et al. Among authors: violette sm. JCI Insight. 2017 May 4;2(9):e86608. doi: 10.1172/jci.insight.86608. eCollection 2017 May 4. JCI Insight. 2017. PMID: 28469072 Free PMC article.
Fibronectin-guided migration of carcinoma collectives.
Gopal S, Veracini L, Grall D, Butori C, Schaub S, Audebert S, Camoin L, Baudelet E, Radwanska A, Beghelli-de la Forest Divonne S, Violette SM, Weinreb PH, Rekima S, Ilie M, Sudaka A, Hofman P, Van Obberghen-Schilling E. Gopal S, et al. Among authors: violette sm. Nat Commun. 2017 Jan 19;8:14105. doi: 10.1038/ncomms14105. Nat Commun. 2017. PMID: 28102238 Free PMC article.
Inhibition of αvβ5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury.
McCurley A, Alimperti S, Campos-Bilderback SB, Sandoval RM, Calvino JE, Reynolds TL, Quigley C, Mugford JW, Polacheck WJ, Gomez IG, Dovey J, Marsh G, Huang A, Qian F, Weinreb PH, Dolinski BM, Moore S, Duffield JS, Chen CS, Molitoris BA, Violette SM, Crackower MA. McCurley A, et al. Among authors: violette sm. J Am Soc Nephrol. 2017 Jun;28(6):1741-1752. doi: 10.1681/ASN.2016020200. Epub 2017 Jan 6. J Am Soc Nephrol. 2017. PMID: 28062569 Free PMC article.
65 results