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432 results

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Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response.
Dela Cruz Chuh J, Go M, Chen Y, Guo J, Rafidi H, Mandikian D, Sun Y, Lin Z, Schneider K, Zhang P, Vij R, Sharpnack D, Chan P, de la Cruz C, Sadowsky J, Seshasayee D, Koerber JT, Pillow TH, Phillips GD, Rowntree RK, Boswell CA, Kozak KR, Polson AG, Polakis P, Yu SF, Dragovich PS, Agard NJ. Dela Cruz Chuh J, et al. Among authors: vij r. MAbs. 2021 Jan-Dec;13(1):1862452. doi: 10.1080/19420862.2020.1862452. MAbs. 2021. PMID: 33382956 Free PMC article.
Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer.
Junttila MR, Mao W, Wang X, Wang BE, Pham T, Flygare J, Yu SF, Yee S, Goldenberg D, Fields C, Eastham-Anderson J, Singh M, Vij R, Hongo JA, Firestein R, Schutten M, Flagella K, Polakis P, Polson AG. Junttila MR, et al. Among authors: vij r. Sci Transl Med. 2015 Nov 18;7(314):314ra186. doi: 10.1126/scitranslmed.aac7433. Sci Transl Med. 2015. PMID: 26582901
An Anti-CLL-1 Antibody-Drug Conjugate for the Treatment of Acute Myeloid Leukemia.
Zheng B, Yu SF, Del Rosario G, Leong SR, Lee GY, Vij R, Chiu C, Liang WC, Wu Y, Chalouni C, Sadowsky J, Clark V, Hendricks A, Poon KA, Chu W, Pillow T, Schutten MM, Flygare J, Polson AG. Zheng B, et al. Among authors: vij r. Clin Cancer Res. 2019 Feb 15;25(4):1358-1368. doi: 10.1158/1078-0432.CCR-18-0333. Epub 2018 Jun 29. Clin Cancer Res. 2019. PMID: 29959143
Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal.
Storek KM, Auerbach MR, Shi H, Garcia NK, Sun D, Nickerson NN, Vij R, Lin Z, Chiang N, Schneider K, Wecksler AT, Skippington E, Nakamura G, Seshasayee D, Koerber JT, Payandeh J, Smith PA, Rutherford ST. Storek KM, et al. Among authors: vij r. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3692-3697. doi: 10.1073/pnas.1800043115. Epub 2018 Mar 19. Proc Natl Acad Sci U S A. 2018. PMID: 29555747 Free PMC article.
A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies.
Vij R, Lin Z, Chiang N, Vernes JM, Storek KM, Park S, Chan J, Meng YG, Comps-Agrar L, Luan P, Lee S, Schneider K, Bevers J 3rd, Zilberleyb I, Tam C, Koth CM, Xu M, Gill A, Auerbach MR, Smith PA, Rutherford ST, Nakamura G, Seshasayee D, Payandeh J, Koerber JT. Vij R, et al. Sci Rep. 2018 May 8;8(1):7136. doi: 10.1038/s41598-018-25609-z. Sci Rep. 2018. PMID: 29740124 Free PMC article.
Massive antibody discovery used to probe structure-function relationships of the essential outer membrane protein LptD.
Storek KM, Chan J, Vij R, Chiang N, Lin Z, Bevers J 3rd, Koth CM, Vernes JM, Meng YG, Yin J, Wallweber H, Dalmas O, Shriver S, Tam C, Schneider K, Seshasayee D, Nakamura G, Smith PA, Payandeh J, Koerber JT, Comps-Agrar L, Rutherford ST. Storek KM, et al. Among authors: vij r. Elife. 2019 Jun 25;8:e46258. doi: 10.7554/eLife.46258. Elife. 2019. PMID: 31237236 Free PMC article.
432 results