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Axitinib with or without dose titration for first-line metastatic renal-cell carcinoma: a randomised double-blind phase 2 trial.
Rini BI, Melichar B, Ueda T, Grünwald V, Fishman MN, Arranz JA, Bair AH, Pithavala YK, Andrews GI, Pavlov D, Kim S, Jonasch E. Rini BI, et al. Among authors: pithavala yk. Lancet Oncol. 2013 Nov;14(12):1233-42. doi: 10.1016/S1470-2045(13)70464-9. Epub 2013 Oct 18. Lancet Oncol. 2013. PMID: 24140184 Free PMC article. Clinical Trial.
Effect of Renal Impairment on the Pharmacokinetics and Safety of Axitinib.
Chen Y, Rini BI, Motzer RJ, Dutcher JP, Rixe O, Wilding G, Stadler WM, Tarazi J, Garrett M, Pithavala YK. Chen Y, et al. Among authors: pithavala yk. Target Oncol. 2016 Apr;11(2):229-34. doi: 10.1007/s11523-015-0389-2. Target Oncol. 2016. PMID: 26400730 Free PMC article.
A Phase II trial of axitinib in patients with various histologic subtypes of advanced thyroid cancer: long-term outcomes and pharmacokinetic/pharmacodynamic analyses.
Cohen EE, Tortorici M, Kim S, Ingrosso A, Pithavala YK, Bycott P. Cohen EE, et al. Among authors: pithavala yk. Cancer Chemother Pharmacol. 2014 Dec;74(6):1261-70. doi: 10.1007/s00280-014-2604-8. Epub 2014 Oct 15. Cancer Chemother Pharmacol. 2014. PMID: 25315258 Free PMC article. Clinical Trial.
Efficacy of gemcitabine plus axitinib compared with gemcitabine alone in patients with advanced pancreatic cancer: an open-label randomised phase II study.
Spano JP, Chodkiewicz C, Maurel J, Wong R, Wasan H, Barone C, Létourneau R, Bajetta E, Pithavala Y, Bycott P, Trask P, Liau K, Ricart AD, Kim S, Rixe O. Spano JP, et al. Lancet. 2008 Jun 21;371(9630):2101-8. doi: 10.1016/S0140-6736(08)60661-3. Epub 2008 May 29. Lancet. 2008. PMID: 18514303 Clinical Trial.
Treatment of advanced thyroid cancer with axitinib: Phase 2 study with pharmacokinetic/pharmacodynamic and quality-of-life assessments.
Locati LD, Licitra L, Agate L, Ou SH, Boucher A, Jarzab B, Qin S, Kane MA, Wirth LJ, Chen C, Kim S, Ingrosso A, Pithavala YK, Bycott P, Cohen EE. Locati LD, et al. Among authors: pithavala yk. Cancer. 2014 Sep 1;120(17):2694-703. doi: 10.1002/cncr.28766. Epub 2014 May 20. Cancer. 2014. PMID: 24844950 Free article. Clinical Trial.
Pharmacokinetics of single-agent axitinib across multiple solid tumor types.
Tortorici MA, Cohen EE, Pithavala YK, Garrett M, Ruiz-Garcia A, Kim S, Fruehauf JP. Tortorici MA, et al. Among authors: pithavala yk. Cancer Chemother Pharmacol. 2014 Dec;74(6):1279-89. doi: 10.1007/s00280-014-2606-6. Epub 2014 Oct 22. Cancer Chemother Pharmacol. 2014. PMID: 25336084
55 results