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Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.
Fullerton MD, Galic S, Marcinko K, Sikkema S, Pulinilkunnil T, Chen ZP, O'Neill HM, Ford RJ, Palanivel R, O'Brien M, Hardie DG, Macaulay SL, Schertzer JD, Dyck JR, van Denderen BJ, Kemp BE, Steinberg GR. Fullerton MD, et al. Nat Med. 2013 Dec;19(12):1649-54. doi: 10.1038/nm.3372. Epub 2013 Nov 3. Nat Med. 2013. PMID: 24185692 Free PMC article.
The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs.
Dite TA, Ling NXY, Scott JW, Hoque A, Galic S, Parker BL, Ngoei KRW, Langendorf CG, O'Brien MT, Kundu M, Viollet B, Steinberg GR, Sakamoto K, Kemp BE, Oakhill JS. Dite TA, et al. Nat Commun. 2017 Sep 18;8(1):571. doi: 10.1038/s41467-017-00628-y. Nat Commun. 2017. PMID: 28924239 Free PMC article.
CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins.
Langendorf CG, O'Brien MT, Ngoei KRW, McAloon LM, Dhagat U, Hoque A, Ling NXY, Dite TA, Galic S, Loh K, Parker MW, Oakhill JS, Kemp BE, Scott JW. Langendorf CG, et al. J Biol Chem. 2020 Nov 27;295(48):16239-16250. doi: 10.1074/jbc.RA120.013756. Epub 2020 Sep 9. J Biol Chem. 2020. PMID: 32913128 Free PMC article.
Safety of pembrolizumab as adjuvant therapy in a pooled analysis of phase 3 clinical trials of melanoma, non-small cell lung cancer, and renal cell carcinoma.
Luke JJ, Long GV, Robert C, Carlino MS, Choueiri TK, Haas NB, O'Brien M, Paz-Ares L, Peters S, Powles T, Leiby MA, Lin J, Zhao Y, Krepler C, Perini RF, Catherine Pietanza M, Samkari A, Gruber T, Ibrahim N, Eggermont AMM. Luke JJ, et al. Among authors: o brien m. Eur J Cancer. 2024 May 31;207:114146. doi: 10.1016/j.ejca.2024.114146. Online ahead of print. Eur J Cancer. 2024. PMID: 38838446
"I could not find the strength to resist the pressure of the medical staff, to refuse to give commercial milk formula": a qualitative study on effects of the war on Ukrainian women's infant feeding.
Iellamo A, Wong CM, Bilukha O, Smith JP, Ververs M, Gribble K, Walczak B, Wesolowska A, Al Samman S, O'Brien M, Brown AN, Stillman T, Thomas B. Iellamo A, et al. Among authors: o brien m. Front Nutr. 2024 May 17;11:1225940. doi: 10.3389/fnut.2024.1225940. eCollection 2024. Front Nutr. 2024. PMID: 38826579 Free PMC article.
3,335 results