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[1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains.
Fedorov O, Lingard H, Wells C, Monteiro OP, Picaud S, Keates T, Yapp C, Philpott M, Martin SJ, Felletar I, Marsden BD, Filippakopoulos P, Müller S, Knapp S, Brennan PE. Fedorov O, et al. Among authors: muller s. J Med Chem. 2014 Jan 23;57(2):462-76. doi: 10.1021/jm401568s. Epub 2013 Dec 30. J Med Chem. 2014. PMID: 24313754 Free PMC article.
The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.
Gileadi O, Knapp S, Lee WH, Marsden BD, Müller S, Niesen FH, Kavanagh KL, Ball LJ, von Delft F, Doyle DA, Oppermann UC, Sundström M. Gileadi O, et al. Among authors: muller s. J Struct Funct Genomics. 2007 Sep;8(2-3):107-19. doi: 10.1007/s10969-007-9027-2. Epub 2007 Oct 12. J Struct Funct Genomics. 2007. PMID: 17932789 Free PMC article. Review.
Structural and functional characterization of the human protein kinase ASK1.
Bunkoczi G, Salah E, Filippakopoulos P, Fedorov O, Müller S, Sobott F, Parker SA, Zhang H, Min W, Turk BE, Knapp S. Bunkoczi G, et al. Among authors: muller s. Structure. 2007 Oct;15(10):1215-26. doi: 10.1016/j.str.2007.08.011. Structure. 2007. PMID: 17937911 Free PMC article.
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S. Fedorov O, et al. Among authors: muller s. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20523-8. doi: 10.1073/pnas.0708800104. Epub 2007 Dec 11. Proc Natl Acad Sci U S A. 2007. PMID: 18077363 Free PMC article.
SH2 domains: modulators of nonreceptor tyrosine kinase activity.
Filippakopoulos P, Müller S, Knapp S. Filippakopoulos P, et al. Among authors: muller s. Curr Opin Struct Biol. 2009 Dec;19(6):643-9. doi: 10.1016/j.sbi.2009.10.001. Epub 2009 Nov 18. Curr Opin Struct Biol. 2009. PMID: 19926274 Free PMC article. Review.
The (un)targeted cancer kinome.
Fedorov O, Müller S, Knapp S. Fedorov O, et al. Among authors: muller s. Nat Chem Biol. 2010 Mar;6(3):166-169. doi: 10.1038/nchembio.297. Nat Chem Biol. 2010. PMID: 20154661 No abstract available.
Bromodomains as therapeutic targets.
Muller S, Filippakopoulos P, Knapp S. Muller S, et al. Expert Rev Mol Med. 2011 Sep 13;13:e29. doi: 10.1017/S1462399411001992. Expert Rev Mol Med. 2011. PMID: 21933453 Free PMC article. Review.
Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation.
Keates T, Cooper CD, Savitsky P, Allerston CK, Phillips C, Hammarström M, Daga N, Berridge G, Mahajan P, Burgess-Brown NA, Müller S, Gräslund S, Gileadi O. Keates T, et al. Among authors: muller s. N Biotechnol. 2012 Jun 15;29(5):515-25. doi: 10.1016/j.nbt.2011.10.007. Epub 2011 Oct 19. N Biotechnol. 2012. PMID: 22027370 Free PMC article.
5,541 results