Schwank G - Search Results

1

Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients.

Schwank G, Koo BK, Sasselli V, Dekkers JF, Heo I, Demircan T, Sasaki N, Boymans S, Cuppen E, van der Ent CK, Nieuwenhuis EE, Beekman JM, Clevers H. Schwank G, et al. Cell Stem Cell. 2013 Dec 5;13(6):653-8. doi: 10.1016/j.stem.2013.11.002. Cell Stem Cell. 2013. PMID: 24315439 Free article.

2

Generation of BAC transgenic epithelial organoids.

Schwank G, Andersson-Rolf A, Koo BK, Sasaki N, Clevers H. Schwank G, et al. PLoS One. 2013 Oct 18;8(10):e76871. doi: 10.1371/journal.pone.0076871. eCollection 2013. PLoS One. 2013. PMID: 24204693 Free PMC article.

3

CRISPR/Cas9-Mediated Genome Editing of Mouse Small Intestinal Organoids.

Schwank G, Clevers H. Schwank G, et al. Methods Mol Biol. 2016;1422:3-11. doi: 10.1007/978-1-4939-3603-8_1. Methods Mol Biol. 2016. PMID: 27246017

4

Sequential cancer mutations in cultured human intestinal stem cells.

Drost J, van Jaarsveld RH, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, Sachs N, Overmeer RM, Offerhaus GJ, Begthel H, Korving J, van de Wetering M, Schwank G, Logtenberg M, Cuppen E, Snippert HJ, Medema JP, Kops GJ, Clevers H. Drost J, et al. Among authors: schwank g. Nature. 2015 May 7;521(7550):43-7. doi: 10.1038/nature14415. Epub 2015 Apr 29. Nature. 2015. PMID: 25924068

5

Tissue-specific mutation accumulation in human adult stem cells during life.

Blokzijl F, de Ligt J, Jager M, Sasselli V, Roerink S, Sasaki N, Huch M, Boymans S, Kuijk E, Prins P, Nijman IJ, Martincorena I, Mokry M, Wiegerinck CL, Middendorp S, Sato T, Schwank G, Nieuwenhuis EE, Verstegen MM, van der Laan LJ, de Jonge J, IJzermans JN, Vries RG, van de Wetering M, Stratton MR, Clevers H, Cuppen E, van Boxtel R. Blokzijl F, et al. Among authors: schwank g. Nature. 2016 Oct 13;538(7624):260-264. doi: 10.1038/nature19768. Epub 2016 Oct 3. Nature. 2016. PMID: 27698416 Free PMC article.

6

Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance.

Ringel T, Frey N, Ringnalda F, Janjuha S, Cherkaoui S, Butz S, Srivatsa S, Pirkl M, Russo G, Villiger L, Rogler G, Clevers H, Beerenwinkel N, Zamboni N, Baubec T, Schwank G. Ringel T, et al. Among authors: schwank g. Cell Stem Cell. 2020 Mar 5;26(3):431-440.e8. doi: 10.1016/j.stem.2020.02.007. Cell Stem Cell. 2020. PMID: 32142663 Free article.

7

Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ.

Farin HF, Karthaus WR, Kujala P, Rakhshandehroo M, Schwank G, Vries RG, Kalkhoven E, Nieuwenhuis EE, Clevers H. Farin HF, et al. Among authors: schwank g. J Exp Med. 2014 Jun 30;211(7):1393-405. doi: 10.1084/jem.20130753. J Exp Med. 2014. PMID: 24980747 Free PMC article.

8

Advances in therapeutic CRISPR/Cas9 genome editing.

Savić N, Schwank G. Savić N, et al. Among authors: schwank g. Transl Res. 2016 Feb;168:15-21. doi: 10.1016/j.trsl.2015.09.008. Epub 2015 Sep 26. Transl Res. 2016. PMID: 26470680 Free article. Review.

9

Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair.

Savic N, Ringnalda FC, Lindsay H, Berk C, Bargsten K, Li Y, Neri D, Robinson MD, Ciaudo C, Hall J, Jinek M, Schwank G. Savic N, et al. Among authors: schwank g. Elife. 2018 May 29;7:e33761. doi: 10.7554/eLife.33761. Elife. 2018. PMID: 29809142 Free PMC article.

10

Predicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens.

Marquart KF, Allam A, Janjuha S, Sintsova A, Villiger L, Frey N, Krauthammer M, Schwank G. Marquart KF, et al. Among authors: schwank g. Nat Commun. 2021 Aug 25;12(1):5114. doi: 10.1038/s41467-021-25375-z. Nat Commun. 2021. PMID: 34433819 Free PMC article.

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