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Treatment response in Kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G.
Ogata S, Shimizu C, Franco A, Touma R, Kanegaye JT, Choudhury BP, Naidu NN, Kanda Y, Hoang LT, Hibberd ML, Tremoulet AH, Varki A, Burns JC. Ogata S, et al. Among authors: varki a. PLoS One. 2013 Dec 6;8(12):e81448. doi: 10.1371/journal.pone.0081448. eCollection 2013. PLoS One. 2013. PMID: 24324693 Free PMC article.
Metabolism of vertebrate amino sugars with N-glycolyl groups: incorporation of N-glycolylhexosamines into mammalian glycans by feeding N-glycolylgalactosamine.
Bergfeld AK, Pearce OM, Diaz SL, Lawrence R, Vocadlo DJ, Choudhury B, Esko JD, Varki A. Bergfeld AK, et al. Among authors: varki a. J Biol Chem. 2012 Aug 17;287(34):28898-916. doi: 10.1074/jbc.M112.363499. Epub 2012 Jun 12. J Biol Chem. 2012. PMID: 22692203 Free PMC article.
To date, hydroxylation of CMP-Neu5Ac resulting in the conversion into CMP-Neu5Gc is the only known enzymatic reaction in mammals to synthesize a monosaccharide carrying an N-glycolyl group. In our accompanying paper (Bergfeld, A. K., Pearce, O. M., Diaz, S. L., Pham …
To date, hydroxylation of CMP-Neu5Ac resulting in the conversion into CMP-Neu5Gc is the only known enzymatic reaction in mammals to synthesi …
Physiological Exploration of the Long Term Evolutionary Selection against Expression of N-Glycolylneuraminic Acid in the Brain.
Naito-Matsui Y, Davies LR, Takematsu H, Chou HH, Tangvoranuntakul P, Carlin AF, Verhagen A, Heyser CJ, Yoo SW, Choudhury B, Paton JC, Paton AW, Varki NM, Schnaar RL, Varki A. Naito-Matsui Y, et al. Among authors: varki a, varki nm. J Biol Chem. 2017 Feb 17;292(7):2557-2570. doi: 10.1074/jbc.M116.768531. Epub 2017 Jan 3. J Biol Chem. 2017. PMID: 28049733 Free PMC article.
Redox-Controlled Site-Specific α2-6-Sialylation.
Lu N, Ye J, Cheng J, Sasmal A, Liu CC, Yao W, Yan J, Khan N, Yi W, Varki A, Cao H. Lu N, et al. Among authors: varki a. J Am Chem Soc. 2019 Mar 20;141(11):4547-4552. doi: 10.1021/jacs.9b00044. Epub 2019 Mar 11. J Am Chem Soc. 2019. PMID: 30843692 Free PMC article.
Exploring the Impact of Ketodeoxynonulosonic Acid in Host-Pathogen Interactions Using Uptake and Surface Display by Nontypeable Haemophilus influenzae.
Saha S, Coady A, Sasmal A, Kawanishi K, Choudhury B, Yu H, Sorensen RU, Inostroza J, Schoenhofen IC, Chen X, Münster-Kühnel A, Sato C, Kitajima K, Ram S, Nizet V, Varki A. Saha S, et al. Among authors: varki a. mBio. 2021 Jan 19;12(1):e03226-20. doi: 10.1128/mBio.03226-20. mBio. 2021. PMID: 33468699 Free PMC article.
560 results