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243 results

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Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial.
Palfi S, Gurruchaga JM, Ralph GS, Lepetit H, Lavisse S, Buttery PC, Watts C, Miskin J, Kelleher M, Deeley S, Iwamuro H, Lefaucheur JP, Thiriez C, Fenelon G, Lucas C, Brugières P, Gabriel I, Abhay K, Drouot X, Tani N, Kas A, Ghaleh B, Le Corvoisier P, Dolphin P, Breen DP, Mason S, Guzman NV, Mazarakis ND, Radcliffe PA, Harrop R, Kingsman SM, Rascol O, Naylor S, Barker RA, Hantraye P, Remy P, Cesaro P, Mitrophanous KA. Palfi S, et al. Among authors: hantraye p. Lancet. 2014 Mar 29;383(9923):1138-46. doi: 10.1016/S0140-6736(13)61939-X. Epub 2014 Jan 10. Lancet. 2014. PMID: 24412048 Clinical Trial.
Long-Term Follow-Up of a Phase I/II Study of ProSavin, a Lentiviral Vector Gene Therapy for Parkinson's Disease.
Palfi S, Gurruchaga JM, Lepetit H, Howard K, Ralph GS, Mason S, Gouello G, Domenech P, Buttery PC, Hantraye P, Tuckwell NJ, Barker RA, Mitrophanous KA. Palfi S, et al. Among authors: hantraye p. Hum Gene Ther Clin Dev. 2018 Sep;29(3):148-155. doi: 10.1089/humc.2018.081. Hum Gene Ther Clin Dev. 2018. PMID: 30156440 Free PMC article. Clinical Trial.
Gene Therapy for Parkinson's Disease: Preclinical Evaluation of Optimally Configured TH:CH1 Fusion for Maximal Dopamine Synthesis.
Badin RA, Binley K, Van Camp N, Jan C, Gourlay J, Robert C, Gipchtein P, Fayard A, Stewart H, Ralph GS, Lad Y, Kelleher M, Loader J, Hosomi K, Palfi S, Mitrophanous KA, Hantraye P. Badin RA, et al. Among authors: hantraye p. Mol Ther Methods Clin Dev. 2019 Jul 16;14:206-216. doi: 10.1016/j.omtm.2019.07.002. eCollection 2019 Sep 13. Mol Ther Methods Clin Dev. 2019. PMID: 31406701 Free PMC article.
Motor and cognitive improvements in patients with Huntington's disease after neural transplantation.
Bachoud-Lévi AC, Rémy P, Nguyen JP, Brugières P, Lefaucheur JP, Bourdet C, Baudic S, Gaura V, Maison P, Haddad B, Boissé MF, Grandmougin T, Jény R, Bartolomeo P, Dalla Barba G, Degos JD, Lisovoski F, Ergis AM, Pailhous E, Cesaro P, Hantraye P, Peschanski M. Bachoud-Lévi AC, et al. Among authors: hantraye p. Lancet. 2000 Dec 9;356(9246):1975-9. doi: 10.1016/s0140-6736(00)03310-9. Lancet. 2000. PMID: 11130527 Clinical Trial.
Three-dimensional SPACE fluid-attenuated inversion recovery at 3 T to improve subthalamic nucleus lead placement for deep brain stimulation in Parkinson's disease: from preclinical to clinical studies.
Senova S, Hosomi K, Gurruchaga JM, Gouello G, Ouerchefani N, Beaugendre Y, Lepetit H, Lefaucheur JP, Badin RA, Dauguet J, Jan C, Hantraye P, Brugières P, Palfi S. Senova S, et al. Among authors: hantraye p. J Neurosurg. 2016 Aug;125(2):472-80. doi: 10.3171/2015.7.JNS15379. Epub 2016 Jan 8. J Neurosurg. 2016. PMID: 26745490
Decrease of nicotinic receptors in the nigrostriatal system in Parkinson's disease.
Kas A, Bottlaender M, Gallezot JD, Vidailhet M, Villafane G, Grégoire MC, Coulon C, Valette H, Dollé F, Ribeiro MJ, Hantraye P, Remy P. Kas A, et al. Among authors: hantraye p. J Cereb Blood Flow Metab. 2009 Sep;29(9):1601-8. doi: 10.1038/jcbfm.2009.74. Epub 2009 Jun 3. J Cereb Blood Flow Metab. 2009. PMID: 19491921
Increased microglial activation in patients with Parkinson disease using [18F]-DPA714 TSPO PET imaging.
Lavisse S, Goutal S, Wimberley C, Tonietto M, Bottlaender M, Gervais P, Kuhnast B, Peyronneau MA, Barret O, Lagarde J, Sarazin M, Hantraye P, Thiriez C, Remy P. Lavisse S, et al. Among authors: hantraye p. Parkinsonism Relat Disord. 2021 Jan;82:29-36. doi: 10.1016/j.parkreldis.2020.11.011. Epub 2020 Nov 17. Parkinsonism Relat Disord. 2021. PMID: 33242662 Clinical Trial.
243 results