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Translation of TRO40303 from myocardial infarction models to demonstration of safety and tolerance in a randomized Phase I trial.
Le Lamer S, Paradis S, Rahmouni H, Chaimbault C, Michaud M, Culcasi M, Afxantidis J, Latreille M, Berna P, Berdeaux A, Pietri S, Morin D, Donazzolo Y, Abitbol JL, Pruss RM, Schaller S. Le Lamer S, et al. Among authors: paradis s. J Transl Med. 2014 Feb 7;12:38. doi: 10.1186/1479-5876-12-38. J Transl Med. 2014. PMID: 24507657 Free PMC article. Clinical Trial.
TRO40303, a new cardioprotective compound, inhibits mitochondrial permeability transition.
Schaller S, Paradis S, Ngoh GA, Assaly R, Buisson B, Drouot C, Ostuni MA, Lacapere JJ, Bassissi F, Bordet T, Berdeaux A, Jones SP, Morin D, Pruss RM. Schaller S, et al. Among authors: paradis s. J Pharmacol Exp Ther. 2010 Jun;333(3):696-706. doi: 10.1124/jpet.110.167486. Epub 2010 Mar 9. J Pharmacol Exp Ther. 2010. PMID: 20215409 Free article.
94 results