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IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases.
Shen P, Roch T, Lampropoulou V, O'Connor RA, Stervbo U, Hilgenberg E, Ries S, Dang VD, Jaimes Y, Daridon C, Li R, Jouneau L, Boudinot P, Wilantri S, Sakwa I, Miyazaki Y, Leech MD, McPherson RC, Wirtz S, Neurath M, Hoehlig K, Meinl E, Grützkau A, Grün JR, Horn K, Kühl AA, Dörner T, Bar-Or A, Kaufmann SHE, Anderton SM, Fillatreau S. Shen P, et al. Among authors: kuhl aa. Nature. 2014 Mar 20;507(7492):366-370. doi: 10.1038/nature12979. Epub 2014 Feb 23. Nature. 2014. PMID: 24572363 Free PMC article.
The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes.
Stittrich AB, Haftmann C, Sgouroudis E, Kühl AA, Hegazy AN, Panse I, Riedel R, Flossdorf M, Dong J, Fuhrmann F, Heinz GA, Fang Z, Li N, Bissels U, Hatam F, Jahn A, Hammoud B, Matz M, Schulze FM, Baumgrass R, Bosio A, Mollenkopf HJ, Grün J, Thiel A, Chen W, Höfer T, Loddenkemper C, Löhning M, Chang HD, Rajewsky N, Radbruch A, Mashreghi MF. Stittrich AB, et al. Among authors: kuhl aa. Nat Immunol. 2010 Nov;11(11):1057-62. doi: 10.1038/ni.1945. Epub 2010 Oct 10. Nat Immunol. 2010. PMID: 20935646
Reprogrammed quiescent B cells provide an effective cellular therapy against chronic experimental autoimmune encephalomyelitis.
Calderón-Gómez E, Lampropoulou V, Shen P, Neves P, Roch T, Stervbo U, Rutz S, Kühl AA, Heppner FL, Loddenkemper C, Anderton SM, Kanellopoulos JM, Charneau P, Fillatreau S. Calderón-Gómez E, et al. Among authors: kuhl aa. Eur J Immunol. 2011 Jun;41(6):1696-708. doi: 10.1002/eji.201041041. Epub 2011 May 25. Eur J Immunol. 2011. PMID: 21469107 Free PMC article.
Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory.
Okhrimenko A, Grün JR, Westendorf K, Fang Z, Reinke S, von Roth P, Wassilew G, Kühl AA, Kudernatsch R, Demski S, Scheibenbogen C, Tokoyoda K, McGrath MA, Raftery MJ, Schönrich G, Serra A, Chang HD, Radbruch A, Dong J. Okhrimenko A, et al. Among authors: kuhl aa. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9229-34. doi: 10.1073/pnas.1318731111. Epub 2014 Jun 10. Proc Natl Acad Sci U S A. 2014. PMID: 24927527 Free PMC article. Clinical Trial.
Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas.
Duque-Correa MA, Kühl AA, Rodriguez PC, Zedler U, Schommer-Leitner S, Rao M, Weiner J 3rd, Hurwitz R, Qualls JE, Kosmiadi GA, Murray PJ, Kaufmann SH, Reece ST. Duque-Correa MA, et al. Among authors: kuhl aa. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):E4024-32. doi: 10.1073/pnas.1408839111. Epub 2014 Sep 8. Proc Natl Acad Sci U S A. 2014. PMID: 25201986 Free PMC article.
223 results