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Within-host whole-genome deep sequencing and diversity analysis of human respiratory syncytial virus infection reveals dynamics of genomic diversity in the absence and presence of immune pressure.
Grad YH, Newman R, Zody M, Yang X, Murphy R, Qu J, Malboeuf CM, Levin JZ, Lipsitch M, DeVincenzo J. Grad YH, et al. Among authors: zody m. J Virol. 2014 Jul;88(13):7286-93. doi: 10.1128/JVI.00038-14. Epub 2014 Apr 16. J Virol. 2014. PMID: 24741088 Free PMC article.
Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection.
Henn MR, Boutwell CL, Charlebois P, Lennon NJ, Power KA, Macalalad AR, Berlin AM, Malboeuf CM, Ryan EM, Gnerre S, Zody MC, Erlich RL, Green LM, Berical A, Wang Y, Casali M, Streeck H, Bloom AK, Dudek T, Tully D, Newman R, Axten KL, Gladden AD, Battis L, Kemper M, Zeng Q, Shea TP, Gujja S, Zedlack C, Gasser O, Brander C, Hess C, Günthard HF, Brumme ZL, Brumme CJ, Bazner S, Rychert J, Tinsley JP, Mayer KH, Rosenberg E, Pereyra F, Levin JZ, Young SK, Jessen H, Altfeld M, Birren BW, Walker BD, Allen TM. Henn MR, et al. Among authors: zody mc. PLoS Pathog. 2012;8(3):e1002529. doi: 10.1371/journal.ppat.1002529. Epub 2012 Mar 8. PLoS Pathog. 2012. PMID: 22412369 Free PMC article.
Highly sensitive and specific detection of rare variants in mixed viral populations from massively parallel sequence data.
Macalalad AR, Zody MC, Charlebois P, Lennon NJ, Newman RM, Malboeuf CM, Ryan EM, Boutwell CL, Power KA, Brackney DE, Pesko KN, Levin JZ, Ebel GD, Allen TM, Birren BW, Henn MR. Macalalad AR, et al. Among authors: zody mc. PLoS Comput Biol. 2012;8(3):e1002417. doi: 10.1371/journal.pcbi.1002417. Epub 2012 Mar 15. PLoS Comput Biol. 2012. PMID: 22438797 Free PMC article.
De novo assembly of highly diverse viral populations.
Yang X, Charlebois P, Gnerre S, Coole MG, Lennon NJ, Levin JZ, Qu J, Ryan EM, Zody MC, Henn MR. Yang X, et al. Among authors: zody mc. BMC Genomics. 2012 Sep 13;13:475. doi: 10.1186/1471-2164-13-475. BMC Genomics. 2012. PMID: 22974120 Free PMC article.
Whole genome pyrosequencing of rare hepatitis C virus genotypes enhances subtype classification and identification of naturally occurring drug resistance variants.
Newman RM, Kuntzen T, Weiner B, Berical A, Charlebois P, Kuiken C, Murphy DG, Simmonds P, Bennett P, Lennon NJ, Birren BW, Zody MC, Allen TM, Henn MR. Newman RM, et al. Among authors: zody mc. J Infect Dis. 2013 Jul;208(1):17-31. doi: 10.1093/infdis/jis679. Epub 2012 Nov 6. J Infect Dis. 2013. PMID: 23136221 Free PMC article.
V-Phaser 2: variant inference for viral populations.
Yang X, Charlebois P, Macalalad A, Henn MR, Zody MC. Yang X, et al. BMC Genomics. 2013 Oct 3;14:674. doi: 10.1186/1471-2164-14-674. BMC Genomics. 2013. PMID: 24088188 Free PMC article.
133 results