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Tracing PAKs from GI inflammation to cancer.
Dammann K, Khare V, Gasche C. Dammann K, et al. Gut. 2014 Jul;63(7):1173-84. doi: 10.1136/gutjnl-2014-306768. Epub 2014 May 7. Gut. 2014. PMID: 24811999 Free article. Review.
Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1.
Khare V, Lyakhovich A, Dammann K, Lang M, Borgmann M, Tichy B, Pospisilova S, Luciani G, Campregher C, Evstatiev R, Pflueger M, Hundsberger H, Gasche C. Khare V, et al. Among authors: dammann k. Biochem Pharmacol. 2013 Jan 15;85(2):234-44. doi: 10.1016/j.bcp.2012.10.026. Epub 2012 Nov 9. Biochem Pharmacol. 2013. PMID: 23146664 Free PMC article.
PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation.
Dammann K, Khare V, Lang M, Claudel T, Harpain F, Granofszky N, Evstatiev R, Williams JM, Pritchard DM, Watson A, Gasche C. Dammann K, et al. Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2349-60. doi: 10.1016/j.bbamcr.2015.05.031. Epub 2015 May 31. Biochim Biophys Acta. 2015. PMID: 26036343 Free PMC article.
PAK1 promotes intestinal tumor initiation.
Dammann K, Khare V, Harpain F, Lang M, Kurtovic A, Mesteri I, Evstatiev R, Gasche C. Dammann K, et al. Cancer Prev Res (Phila). 2015 Nov;8(11):1093-101. doi: 10.1158/1940-6207.CAPR-15-0205-T. Epub 2015 Aug 24. Cancer Prev Res (Phila). 2015. PMID: 26304465
A Novel PAK1-Notch1 Axis Regulates Crypt Homeostasis in Intestinal Inflammation.
Frick A, Khare V, Jimenez K, Dammann K, Lang M, Krnjic A, Gmainer C, Baumgartner M, Mesteri I, Gasche C. Frick A, et al. Among authors: dammann k. Cell Mol Gastroenterol Hepatol. 2021;11(3):892-907.e1. doi: 10.1016/j.jcmgh.2020.11.001. Epub 2020 Nov 12. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33189893 Free PMC article.
30 results